Hudlicka Olga
Department of Physiology, Medical School, University of Birmingham Birmingham B15 2TT.
Muscles Ligaments Tendons J. 2011 Oct 30;1(1):3-11. Print 2011 Jan.
The role of microcirculation in skeletal muscle is to provide the supply of oxygen and various nutrients and to remove waste products of muscle metabolism. As skeletal muscles are composed of different fibre types, this review tries to elucidate the question of capillary supply and flow with respect to these. It reviews the current knowledge of structure of microcirculation and its nervous, hormonal, and local (myogenic, metabolic and endothelial) control. It also discuss factors involved in the increase in blood flow and changes in microcirculation occurring during muscle contractions, exercise training, muscle hypertrophy and atrophy, hypoxia, ageing, hypertension, diabetes and limited blood supply.
微循环在骨骼肌中的作用是提供氧气和各种营养物质的供应,并清除肌肉代谢的废物。由于骨骼肌由不同的纤维类型组成,本综述试图阐明与这些纤维类型相关的毛细血管供应和血流问题。它回顾了微循环结构及其神经、激素和局部(肌源性、代谢性和内皮性)控制的当前知识。它还讨论了在肌肉收缩、运动训练、肌肉肥大和萎缩、缺氧、衰老、高血压、糖尿病和血液供应受限期间,参与血流量增加和微循环变化的因素。