Godara Navneet, Khullar Megha, Godara Ramya, Singh Virendra
Department of Conservative Dentistry and Endodontics, Jaipur Dental College, Dhand, Rajasthan, India.
Lung India. 2013 Apr;30(2):113-6. doi: 10.4103/0970-2113.110418.
Dry powder inhalers (DPIs) are commonly employed in the management of asthma and other diseases with airway obstruction. A causal relationship of DPI use and occurrence of dental caries has been speculated. The present case-control study was therefore designed to examine the potential link between dental caries and specific use of dry powder inhalers in patients with bronchial asthma.
The present study was conducted on 100 asthmatic patients aged between 10 and 45 years who were using DPIs for at least one year. The control group (n = 100) was selected from non-asthmatic individuals and were matched with the study group with respect to age, gender, and socio-economic status.
The results revealed that asthmatic subjects exhibited higher occurrence of dental caries in comparison to control group, but the difference was statistically non-significant. The mean decayed, missing, and filled teeth (DMFT) indices scores in asthmatic and control group were found to be 1.71 ± 2.34 SD and 1.46 ± 1.89 SD (P = 0.408), respectively. Likewise, the mean decayed, missing, and filled surfaces (DMFS) indices scores in both the groups were 2.41 ± 3.84 SD and 2.34 ± 4.48 SD (P = 0.90). However, increased frequency of DPI use was associated with significant risk of caries (P = 0.01). It has been observed that oral rinsing after an inhaler use limited the occurrence of dental caries to a certain extent although was non significant.
Dry powder inhaler use in patients with bronchial asthma was not associated with significant risk of dental caries.
干粉吸入器（DPI）常用于哮喘及其他气道阻塞性疾病的治疗。有人推测使用DPI与龋齿的发生存在因果关系。因此，本病例对照研究旨在探讨支气管哮喘患者龋齿与特定干粉吸入器使用之间的潜在联系。
本研究对100名年龄在10至45岁之间、使用DPI至少一年的哮喘患者进行。对照组（n = 100）选自非哮喘个体，并在年龄、性别和社会经济地位方面与研究组进行匹配。
结果显示，与对照组相比，哮喘患者龋齿发生率更高，但差异无统计学意义。哮喘组和对照组的龋失补牙（DMFT）指数平均得分分别为1.71±2.34标准差和1.46±1.89标准差（P = 0.408）。同样，两组的龋失补牙面（DMFS）指数平均得分分别为2.41±3.84标准差和2.34±4.48标准差（P = 0.90）。然而，DPI使用频率增加与龋齿风险显著相关（P = 0.01）。据观察，吸入器使用后漱口在一定程度上限制了龋齿的发生，尽管不显著。
支气管哮喘患者使用干粉吸入器与龋齿的显著风险无关。
