Charan Ujwala Priya, Peter C V Dincy, Pulimood Susanne A
Departments of Dermatology, Venereology and Leprosy, Christian Medical College, Vellore, Tamil Nadu, India.
Indian Dermatol Online J. 2013 Apr;4(2):102-5. doi: 10.4103/2229-5178.110629.
Hand eczema is a common disease seen in dermatological practice comprising of a spectrum ranging from mild disease to a severe distressing and chronic course with a negative impact on the quality of life.
To assess the impact of hand eczema severity on quality of life.
Patients with hand eczema were enrolled in a prospective study. Disease severity was assessed by hand eczema severity index (HECSI) score and quality of life by dermatology life quality index (DLQI) questionnaire.
Forty-six patients participated of which 22 (47.8%) were males and 24 (52.2%) females. The commonest age group affected among men and women was 50-59 years (31.8%) and 40-49 years (41.7%) respectively. History of atopy was found in 23.9% and 63% had persistent disease. In 28 (60.9%), the trigger was washing soaps and detergents of which 21 (87.5%) were housewives. Of those employed, 27.7% reported loss of work days. The mean HECSI score was 14.46 (S.D = 20.98) and mean DLQI score was 9.54 (S.D = 5.62). Gender, age, occupation and duration of disease did not significantly affect the quality of life or disease severity. Increased episodes of eczema (>4 episodes/year) showed a statistically significant correlation with DLQI (P value = 0.021). There was no significant correlation between HECSI score and DLQI in this study.
Majority of the patients with hand eczema had a significant impairment of their quality of life. The impairment of quality of life in this study was mainly dependent on increased frequency of the eruptions and not on hand eczema severity.
手部湿疹是皮肤科常见疾病，其病情范围从轻度到严重困扰且病程慢性，对生活质量有负面影响。
评估手部湿疹严重程度对生活质量的影响。
手部湿疹患者纳入一项前瞻性研究。通过手部湿疹严重程度指数（HECSI）评分评估疾病严重程度，通过皮肤病生活质量指数（DLQI）问卷评估生活质量。
46例患者参与研究，其中男性22例（47.8%），女性24例（52.2%）。男性和女性中受影响最常见的年龄组分别为50 - 59岁（31.8%）和40 - 49岁（41.7%）。发现23.9%有特应性病史，63%患有持续性疾病。在28例（60.9%）中，诱发因素是洗涤肥皂和洗涤剂，其中21例（87.5%）是家庭主妇。在就业者中，27.7%报告有工作日损失。平均HECSI评分为14.46（标准差 = 20.98），平均DLQI评分为9.54（标准差 = 5.62）。性别、年龄、职业和病程对生活质量或疾病严重程度无显著影响。湿疹发作次数增加（>4次/年）与DLQI呈统计学显著相关性（P值 = 0.021）。本研究中HECSI评分与DLQI之间无显著相关性。
大多数手部湿疹患者的生活质量有显著受损。本研究中生活质量受损主要取决于皮疹发作频率增加，而非手部湿疹严重程度。
