聚吲哚啉生物碱对大鼠肝癌细胞系的体外细胞毒性。构效关系。
In vitro cytotoxicity of polyindolenine alkaloids on rat hepatoma cell lines. Structure activity relationships.
作者信息
Adjibadé Y, Saad H, Kuballa B, Beck J P, Sévenet T, Cabalion P, Anton R
机构信息
Université Louis Pasteur, Faculté de Pharmacie, Laboratoire de Pharmacognosie, Illkirch, France.
出版信息
J Ethnopharmacol. 1990 May;29(2):127-36. doi: 10.1016/0378-8741(90)90050-4.
PMID:2374427
Abstract
New groups of polyindolenine alkaloids have been isolated from new species of the tribe Psychotriae (Rubiaceae). The cyto-inhibitory effects of these compounds on tumoral cell lines have been thoroughly investigated and thus allow the statement of relationships between some original structural patterns and the observed biological effects.
摘要
从茜草科九节族的新物种中分离出了新的聚吲哚啉生物碱类群。已对这些化合物对肿瘤细胞系的细胞抑制作用进行了全面研究，从而能够阐述一些原始结构模式与所观察到的生物学效应之间的关系。
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