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急性疼痛的大脑特征。

A brain signature for acute pain.

机构信息

Department of Physiology, Feinberg School of Medicine, Northwestern University, 303 E. Chicago Avenue, Tarry Building 5-703, Chicago, IL 60611, USA.

出版信息

Trends Cogn Sci. 2013 Jul;17(7):309-10. doi: 10.1016/j.tics.2013.05.001. Epub 2013 Jun 5.

DOI:10.1016/j.tics.2013.05.001
PMID:23747083
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3733463/
Abstract

Wager and colleagues developed a functional MRI-based spatial and magnitude pattern for perception of acute pain, which seems to generalize across many task conditions and subjects. This is a strong demonstration of the existence of a pain signature and raises important questions regarding what pain and perception are.

摘要

瓦格等人开发了一种基于功能磁共振成像的急性疼痛感知的空间和幅度模式，这种模式似乎在许多任务条件和受试者中都具有普遍性。这有力地证明了疼痛特征的存在，并提出了关于疼痛和感知是什么的重要问题。

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本文引用的文献

1
An fMRI-based neurologic signature of physical pain.基于功能磁共振成像的躯体疼痛神经学特征。
N Engl J Med. 2013 Apr 11;368(15):1388-97. doi: 10.1056/NEJMoa1204471.
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Role of primary somatosensory cortex in the coding of pain.初级躯体感觉皮层在疼痛编码中的作用。
Pain. 2013 Mar;154(3):334-344. doi: 10.1016/j.pain.2012.10.021. Epub 2012 Nov 3.
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A dynamic network perspective of chronic pain.慢性疼痛的动态网络视角。
Neurosci Lett. 2012 Jun 29;520(2):197-203. doi: 10.1016/j.neulet.2012.05.001. Epub 2012 May 8.
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Insights gained into pain processing from patients with focal brain lesions.从有局灶性脑损伤的患者身上获得的关于疼痛处理的见解。
Neurosci Lett. 2012 Jun 29;520(2):188-91. doi: 10.1016/j.neulet.2012.05.007. Epub 2012 May 10.
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Differential fMRI activation to noxious heat and tactile stimuli in parasylvian areas of new world monkeys.新世界猴旁矢状区痛觉和触觉刺激的功能磁共振成像差异激活。
Pain. 2012 Jan;153(1):158-169. doi: 10.1016/j.pain.2011.10.006. Epub 2011 Nov 23.
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Large-scale automated synthesis of human functional neuroimaging data.大规模自动化合成人类功能神经影像学数据。
Nat Methods. 2011 Jun 26;8(8):665-70. doi: 10.1038/nmeth.1635.
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A multisensory investigation of the functional significance of the "pain matrix".多模态研究“疼痛矩阵”的功能意义。
Neuroimage. 2011 Feb 1;54(3):2237-49. doi: 10.1016/j.neuroimage.2010.09.084. Epub 2010 Oct 12.
8
Human brain mechanisms of pain perception and regulation in health and disease.健康与疾病状态下人类大脑对疼痛的感知及调节机制。
Eur J Pain. 2005 Aug;9(4):463-84. doi: 10.1016/j.ejpain.2004.11.001. Epub 2005 Jan 21.