Currently available versions of genome-wide association studies cannot be used to query the common haptoglobin copy number variant.
作者信息
Cahill Leah E, Jensen Majken K, Chasman Daniel I, Hazra Aditi, Levy Andrew P, Rimm Eric B
出版信息
J Am Coll Cardiol. 2013 Aug 27;62(9):860-1. doi: 10.1016/j.jacc.2013.04.079. Epub 2013 Jun 7.
Abstract
摘要
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Currently available versions of genome-wide association studies cannot be used to query the common haptoglobin copy number variant.目前可用的全基因组关联研究版本无法用于查询常见的触珠蛋白拷贝数变异。
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本文引用的文献
1
Genetic analysis of haptoglobin polymorphisms with cardiovascular disease and type 2 diabetes in the Diabetes Heart Study.载脂蛋白 H 多态性与糖尿病心脏研究中心血管疾病和 2 型糖尿病的遗传分析。
Cardiovasc Diabetol. 2013 Feb 11;12:31. doi: 10.1186/1475-2840-12-31.
2
Haptoglobin, the good and the bad: is it evidence based?触珠蛋白：益处与弊端——有循证依据吗？
J Am Coll Cardiol. 2013 Feb 19;61(7):738-40. doi: 10.1016/j.jacc.2012.11.041. Epub 2013 Jan 9.
3
Haptoglobin genotype is a consistent marker of coronary heart disease risk among individuals with elevated glycosylated hemoglobin.糖化血红蛋白升高的个体中，触珠蛋白基因型是冠心病风险的一致标志物。
J Am Coll Cardiol. 2013 Feb 19;61(7):728-37. doi: 10.1016/j.jacc.2012.09.063. Epub 2013 Jan 9.
4
Molecular and population analysis of natural selection on the human haptoglobin duplication.人类触珠蛋白基因复制的自然选择的分子与群体分析
Ann Hum Genet. 2012 Sep;76(5):352-62. doi: 10.1111/j.1469-1809.2012.00716.x. Epub 2012 May 21.
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Protein interaction-based genome-wide analysis of incident coronary heart disease.基于蛋白质相互作用的冠心病发病全基因组分析。
Circ Cardiovasc Genet. 2011 Oct;4(5):549-56. doi: 10.1161/CIRCGENETICS.111.960393. Epub 2011 Aug 31.
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MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes.MaCH：利用序列和基因型数据来估计单倍型和未观测基因型。
Genet Epidemiol. 2010 Dec;34(8):816-34. doi: 10.1002/gepi.20533.
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PLINK: a tool set for whole-genome association and population-based linkage analyses.PLINK：一个用于全基因组关联分析和基于群体的连锁分析的工具集。
Am J Hum Genet. 2007 Sep;81(3):559-75. doi: 10.1086/519795. Epub 2007 Jul 25.
8
Haploview: analysis and visualization of LD and haplotype maps.Haploview：连锁不平衡（LD）和单倍型图谱的分析与可视化
Bioinformatics. 2005 Jan 15;21(2):263-5. doi: 10.1093/bioinformatics/bth457. Epub 2004 Aug 5.
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