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真细菌视紫红质——独特的光传感器和多样的离子泵。

Eubacterial rhodopsins - unique photosensors and diverse ion pumps.

作者信息

Brown Leonid S

机构信息

Department of Physics and Biophysics Interdepartmental Group, University of Guelph, Ontario N1G 2W1, Canada.

出版信息

Biochim Biophys Acta. 2014 May;1837(5):553-61. doi: 10.1016/j.bbabio.2013.05.006. Epub 2013 Jun 6.

DOI:10.1016/j.bbabio.2013.05.006
PMID:23748216
Abstract

Since the discovery of proteorhodopsins, the ubiquitous marine light-driven proton pumps of eubacteria, a large number of other eubacterial rhodopsins with diverse structures and functions have been characterized. Here, we review the body of knowledge accumulated on the four major groups of eubacterial rhodopsins, with the focus on their biophysical characterization. We discuss advances and controversies on the unique eubacterial sensory rhodopsins (as represented by Anabaena sensory rhodopsin), proton-pumping proteorhodopsins and xanthorhodopsins, as well as novel non-proton ion pumps. This article is part of a Special Issue entitled: Retinal Proteins - You can teach an old dog new tricks.

摘要

自从发现了原绿球藻视紫红质(真细菌中普遍存在的光驱动质子泵)以来,大量具有不同结构和功能的其他真细菌视紫红质已得到表征。在此,我们综述了在真细菌视紫红质四大类上积累的知识体系,重点是它们的生物物理特性。我们讨论了独特的真细菌感官视紫红质(以鱼腥藻感官视紫红质为代表)、质子泵原绿球藻视紫红质和黄视紫红质以及新型非质子离子泵方面的进展和争议。本文是名为《视网膜蛋白——老狗也能学新招》特刊的一部分。

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