Ngo Trung P, Dufton John, Stern Paula J, Islam Omar
Canadian Memorial Chiropractic College, Toronto, Ontario, Canada.
J Can Chiropr Assoc. 2013 Jun;57(2):150-5.
Primary spinal cord tumours are rare causes of low back pain but can be a significant cause of morbidity if undiagnosed and untreated. The following is a case of a young male patient presenting with low back pain and radicular symptoms caused by myxopapillary ependymoma.
A nineteen year old male presented to an orthopaedic surgeon with a long history of back pain. He was initially diagnosed with soft tissue injuries and discharged. He began to experience erectile and bowel dysfunction two years later and was re-referred to the orthopaedic surgeon by his family physician but was lost to follow-up. The patient did not present to the surgeon until two years after his symptom profile changed. At that point, MRI examinations revealed a large myxopapillary ependymoma extending from T12 to L4 that was confirmed by a pathologist.
The tumour was surgically resected with subsequent adjuvant radiotherapy. After one year, the patient required continued catheterization and had poor anal tone. His back and leg complaints were almost normal. Follow-up MRI examinations revealed no disease progression or new spinal lesions at 4 years after the initial diagnosis.
The clinical presentation of primary spinal cord tumours is non-specific and can easily be missed. In cases of chronic back pain, signs and symptoms should be regularly monitored for changes indicative of progressive neurological compromise such as sensory, motor and bowel/bladder dysfunction. If there is deterioration of clinical signs and symptoms, a spinal tumour should be considered in the list of differential diagnoses. Delayed diagnosis and treatment of these rare causes of back pain could lead to poor outcomes; therefore, a referral to a surgeon should be done immediately with proper follow up to ensure continuity of care.
原发性脊髓肿瘤是导致腰痛的罕见原因,但如果未被诊断和治疗,可能会成为发病的重要原因。以下是一例年轻男性患者因黏液乳头型室管膜瘤出现腰痛和神经根症状的病例。
一名19岁男性因长期背痛就诊于骨科医生。他最初被诊断为软组织损伤并出院。两年后,他开始出现勃起和肠道功能障碍,其家庭医生将他再次转诊至骨科医生处,但他失访了。直到症状出现变化两年后,该患者才再次就诊于外科医生。此时,MRI检查显示一个从T12延伸至L4的巨大黏液乳头型室管膜瘤,病理学家证实了这一诊断。
肿瘤通过手术切除,随后进行辅助放疗。一年后,患者仍需持续导尿,肛门括约肌张力差。他的背部和腿部不适几乎恢复正常。初次诊断4年后的随访MRI检查显示无疾病进展或新的脊柱病变。
原发性脊髓肿瘤的临床表现不具有特异性,很容易被漏诊。对于慢性背痛患者,应定期监测体征和症状的变化,以发现提示进行性神经功能损害的迹象,如感觉、运动及肠道/膀胱功能障碍。如果临床体征和症状恶化,在鉴别诊断中应考虑脊髓肿瘤。对这些罕见的背痛原因延迟诊断和治疗可能导致不良后果;因此,应立即转诊至外科医生处,并进行适当的随访以确保连续治疗。