Nikolov S, Beltschev B
Institut für Anatomie und Histologie der Medizinischen Hochschule Varna, Bulgarien.
Anat Anz. 1990;170(3-4):265-72.
Fascia transversalis of the dorsal wall of the inguinal canal in direct hernias in senile men was studied by transmission electron microscopy. Collagen microfibrils (CMF) were unevenly arranged and rarely formed compact fibres. Dysplastic CMF with variable diameters and nonuniform profiles were also encountered. There was a marked collagenophagy: in some fibroblasts we observed collagen-containing vacuoles in different stages of microfibrillar degradation. Among CMF matrix vesicles were also detected. These ultrastructural findings are discussed as a morphological substrate leading to supportive and mechanical insufficiency of the fascia transversalis causing herniation. It is concluded also that because of the structural defects of the fascial sheath there is a need of alloplastic reconstruction where Bulgarian-made AMPOXEN tissue can successfully be applied.
通过透射电子显微镜对老年男性腹股沟管后壁直疝患者的腹横筋膜进行了研究。胶原微纤维（CMF）排列不均匀，很少形成致密纤维。还发现了直径可变且轮廓不均匀的发育异常的CMF。存在明显的胶原吞噬现象：在一些成纤维细胞中，我们观察到处于微纤维降解不同阶段的含胶原液泡。在CMF中还检测到了基质小泡。这些超微结构发现被讨论为导致腹横筋膜支持和机械功能不足从而引起疝形成的形态学基础。还得出结论，由于筋膜鞘的结构缺陷，需要进行异体修复，保加利亚制造的AMPOXEN组织可成功应用于此。
