Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Philipps-University Marburg, Marburg, Germany.
Psychooncology. 2013 Dec;22(12):2684-92. doi: 10.1002/pon.3329. Epub 2013 Jun 13.
This pilot intervention study assessed the impact of a 3-week inpatient program for mothers with primary breast cancer and their children. The program combined rehabilitative treatment and preventive, psychosocial, child-centered interventions.
A total of 116 mothers (age 29-57 years, mean = 41.1) with primary, non-metastasized breast cancer completed standardized questionnaires before (Pre1), at the beginning of (Pre2), and at the end of (Post) a 3-week inpatient intervention. The standardized scales included mothers' and children's quality of life and children's psychological symptoms. Mothers' emotional functioning and their 116 children's (age 3-14 years, mean = 7.4; 47% female) psychological health and emotional symptoms were defined as primary outcome measures. A within-subject-control-group design was used to compare changes before the intervention (measurements Pre1-Pre2) to changes during the intervention (measurements Pre2-Post) via dependent one-sided t-tests. Additional exploratory analyses for further outcome variables were performed.
Changes during the intervention period were significantly greater than changes during the waiting period for all primary outcome measures (mothers' emotional functioning: p < 0.0001; children's psychological health: p = 0.0035; and children's emotional symptoms: p = 0.0005).
Data suggest that the family-oriented intervention 'getting well together' seems to be beneficial to mothers' and children's quality of life and psychological well-being. Combining oncological rehabilitation and preventive child-centered interventions might be a feasible approach to supporting breast cancer patients and their children and improving their emotional state. Further research is warranted.
本初步干预研究评估了为患有原发性乳腺癌的母亲及其子女提供为期 3 周的住院治疗方案的影响。该方案结合了康复治疗和预防、心理社会、以儿童为中心的干预措施。
共有 116 名患有原发性、非转移性乳腺癌的母亲(年龄 29-57 岁,平均年龄 41.1 岁)完成了标准化问卷,分别在住院治疗前(Pre1)、开始时(Pre2)和结束时(Post)进行了评估。标准化量表包括母亲和孩子的生活质量以及孩子的心理症状。母亲的情绪功能以及其 116 名儿童(年龄 3-14 岁,平均年龄 7.4 岁;47%为女性)的心理健康和情绪症状被定义为主要的测量指标。使用自身对照控制组设计,通过单侧依赖 t 检验比较干预前(测量 Pre1-Pre2)与干预期间(测量 Pre2-Post)的变化。对其他进一步的结果变量进行了探索性分析。
在干预期间,所有主要结果指标的变化都明显大于等待期的变化(母亲的情绪功能:p<0.0001;儿童的心理健康:p=0.0035;儿童的情绪症状:p=0.0005)。
数据表明,以家庭为导向的干预方案“共同康复”似乎有益于母亲和儿童的生活质量和心理幸福感。将肿瘤康复和预防以儿童为中心的干预措施相结合可能是一种支持乳腺癌患者及其子女、改善其情绪状态的可行方法。需要进一步的研究。