Sukhanov D S
Eksp Klin Farmakol. 2013;76(4):45-8.
The antioxidant properties of remaxol, reamberin and ademetionine have been studied in comparison to 5 % glucose solution in a group of 120 patients with drug-induced liver injury. It is established that the inclusion of this drugs in the composition of complex therapy contributed to restoration of the antioxidant potential of the cells, which was manifested by increased activity of glutathione peroxidase and superoxide dismutase and integral indices of antioxidant protection (total antioxidant capacity and total antioxidant status) with a relative stabilization of the level of glutathione-S-transferase. Maximum pharmacotherapeutic effect with respect to all of the studiea indices has been achieved by the use of remaxol.
在一组120例药物性肝损伤患者中，已将瑞马克索（remaxol）、雷安贝林（reamberin）和腺苷蛋氨酸与5%葡萄糖溶液相比较，研究了它们的抗氧化特性。已确定将这些药物纳入综合治疗方案有助于恢复细胞的抗氧化潜能，这表现为谷胱甘肽过氧化物酶和超氧化物歧化酶活性增加以及抗氧化保护的整体指标（总抗氧化能力和总抗氧化状态），同时谷胱甘肽-S-转移酶水平相对稳定。使用瑞马克索已在所有研究指标方面取得了最大的药物治疗效果。
