• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

中国福氏志贺菌多重耐药非典型变体。

Multidrug-resistant atypical variants of Shigella flexneri in China.

机构信息

Academy of Military Medical Sciences, Beijing, China.

出版信息

Emerg Infect Dis. 2013 Jul;19(7):1147-50. doi: 10.3201/eid1907.111221.

DOI:10.3201/eid1907.111221
PMID:23763754
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3713959/
Abstract

We identified 3 atypical Shigella flexneri varieties in China, including 92 strains with multidrug resistance, distinct pulse types, and a novel sequence type. Atypical varieties were prevalent mainly in developed regions, and 1 variant has become the dominant Shigella spp. serotype in China. Improved surveillance will help guide the prevention and control of shigellosis.

摘要

我们在中国鉴定了 3 种非典型福氏志贺菌，包括 92 株多药耐药、脉冲型明显且新型序列型的菌株。非典型菌株主要在发达地区流行，其中 1 种变异体已成为中国志贺菌血清型的主要优势血清型。加强监测将有助于指导痢疾的防控。

相似文献

1
Multidrug-resistant atypical variants of Shigella flexneri in China.中国福氏志贺菌多重耐药非典型变体。
Emerg Infect Dis. 2013 Jul;19(7):1147-50. doi: 10.3201/eid1907.111221.
2
Dissemination of Multidrug-Resistant and with Class 1, Class 2, and Atypical Class 1 Integrons in China.中国多重耐药和具有 1 类、2 类和非典型 1 类整合子的 传播。
Microb Drug Resist. 2019 Dec;25(10):1465-1474. doi: 10.1089/mdr.2018.0229. Epub 2019 Aug 1.
3
Emergence of a new multidrug-resistant serotype X variant in an epidemic clone of Shigella flexneri.福氏志贺菌流行克隆中新出现的一种耐药性血清型 X 变种。
J Clin Microbiol. 2010 Feb;48(2):419-26. doi: 10.1128/JCM.00614-09. Epub 2009 Dec 2.
4
Genome sequence of Shigella flexneri strain SP1, a diarrheal isolate that encodes an extended-spectrum β-lactamase (ESBL).福氏志贺菌菌株SP1的基因组序列，这是一株编码超广谱β-内酰胺酶（ESBL）的腹泻分离株。
Ann Clin Microbiol Antimicrob. 2017 May 12;16(1):37. doi: 10.1186/s12941-017-0212-2.
5
Rapid emergence of third-generation cephalosporin resistance in Shigella sp. isolated in Andaman and Nicobar Islands, India.印度安达曼和尼科巴群岛分离的志贺菌属中第三代头孢菌素耐药性的快速出现。
Microb Drug Resist. 2011 Jun;17(2):329-32. doi: 10.1089/mdr.2010.0084. Epub 2011 Feb 25.
6
Epidemiological characterization of resistance and PCR typing of Shigella flexneri and Shigella sonnei strains isolated from bacillary dysentery cases in Southeast Brazil.从巴西东南部细菌性痢疾病例中分离出的福氏志贺菌和宋内志贺菌菌株的耐药性流行病学特征及PCR分型
Braz J Med Biol Res. 2007 Feb;40(2):249-58. doi: 10.1590/s0100-879x2007000200012.
7
Antimicrobial Resistance of Shigella flexneri Serotype 1b Isolates in China.中国福氏志贺菌1b型菌株的抗菌药物耐药性
PLoS One. 2015 Jun 3;10(6):e0129009. doi: 10.1371/journal.pone.0129009. eCollection 2015.
8
Molecular characterization and analysis of high-level multidrug-resistance of Shigella flexneri serotype 4s strains from China.中国福氏 4 型志贺菌高水平多重耐药株的分子特征分析及其耐药机制研究
Sci Rep. 2016 Jul 4;6:29124. doi: 10.1038/srep29124.
9
Genomic portrait of the evolution and epidemic spread of a recently emerged multidrug-resistant Shigella flexneri clone in China.中国近期出现的多重耐药福氏志贺菌克隆株进化及流行传播的基因组图谱
J Clin Microbiol. 2014 Apr;52(4):1119-26. doi: 10.1128/JCM.02669-13. Epub 2014 Jan 22.
10
IncFII plasmid carrying antimicrobial resistance genes in Shigella flexneri: Vehicle for dissemination.携带抗菌药物耐药基因的 IncFII 质粒在福氏志贺菌中的流行：传播载体。
J Glob Antimicrob Resist. 2019 Mar;16:215-219. doi: 10.1016/j.jgar.2018.10.014. Epub 2018 Oct 18.

引用本文的文献

1
Analyzing in Wuhan: Serotypes, Antimicrobial Resistance, and Public Health Implications.武汉分析：血清型、抗菌药物耐药性及对公共卫生的影响
Infect Drug Resist. 2025 Jul 28;18:3745-3760. doi: 10.2147/IDR.S522808. eCollection 2025.
2
High-Throughput Luminescence-Based Serum Bactericidal Assay Optimization and Characterization to Assess Human Sera Functionality Against Multiple Serotypes.高通量基于发光的血清杀菌测定优化和特性评估，以评估人类血清针对多种血清型的功能。
Int J Mol Sci. 2024 Oct 16;25(20):11123. doi: 10.3390/ijms252011123.
3
Toward a Vaccine: Opportunities and Challenges to Fight an Antimicrobial-Resistant Pathogen.迈向疫苗：应对抗微生物药物耐药性病原体的机遇与挑战。
Int J Mol Sci. 2023 Feb 28;24(5):4649. doi: 10.3390/ijms24054649.
4
Clonal serotype 1c multidrug-resistant detected in multiple institutions by sentinel-site sequencing.通过哨点测序在多个机构检测到克隆血清型1c多重耐药菌。
Front Med (Lausanne). 2022 Aug 1;9:964640. doi: 10.3389/fmed.2022.964640. eCollection 2022.
5
Proteome based mapping and molecular docking revealed DnaA as a potential drug target against .基于蛋白质组的图谱绘制和分子对接表明，DnaA是一种针对……的潜在药物靶点。
Saudi J Biol Sci. 2022 Feb;29(2):1147-1159. doi: 10.1016/j.sjbs.2021.09.051. Epub 2021 Oct 1.
6
: Antibiotic-Resistance Mechanisms And New Horizons For Treatment.抗生素耐药机制与治疗新视野
Infect Drug Resist. 2019 Oct 7;12:3137-3167. doi: 10.2147/IDR.S219755. eCollection 2019.
7
Antimicrobial resistance and genetic characterization of Shigella spp. in Shanxi Province, China, during 2006-2016.2006-2016 年中国山西省志贺氏菌的耐药性及遗传特征分析。
BMC Microbiol. 2019 May 29;19(1):116. doi: 10.1186/s12866-019-1495-6.
8
Characterization and Genomic Analysis of SFPH2, a Novel Infecting .新型感染因子SFPH2的特性及基因组分析
Front Microbiol. 2018 Dec 14;9:3027. doi: 10.3389/fmicb.2018.03027. eCollection 2018.
9
Dominant serotype distribution and antimicrobial resistance profile of Shigella spp. in Xinjiang, China.中国新疆地区志贺氏菌血清型分布及耐药谱分析。
PLoS One. 2018 Apr 3;13(4):e0195259. doi: 10.1371/journal.pone.0195259. eCollection 2018.
10
Shigella flexneri serotype 1c derived from serotype 1a by acquisition of gtrIC gene cluster via a bacteriophage.福氏志贺菌1c血清型是通过噬菌体获得gtrIC基因簇，从1a血清型衍生而来。
BMC Microbiol. 2016 Jun 27;16(1):127. doi: 10.1186/s12866-016-0746-z.

本文引用的文献

1
Rapid emergence of third-generation cephalosporin resistance in Shigella sp. isolated in Andaman and Nicobar Islands, India.印度安达曼和尼科巴群岛分离的志贺菌属中第三代头孢菌素耐药性的快速出现。
Microb Drug Resist. 2011 Jun;17(2):329-32. doi: 10.1089/mdr.2010.0084. Epub 2011 Feb 25.
2
Emergence of a novel Shigella flexneri serotype 4s strain that evolved from a serotype X variant in China.中国新型福氏 4 型志贺菌血清型菌株的出现，该菌株是由血清型 X 变体进化而来。
J Clin Microbiol. 2011 Mar;49(3):1148-50. doi: 10.1128/JCM.01946-10. Epub 2010 Dec 22.
3
Emergence of a new multidrug-resistant serotype X variant in an epidemic clone of Shigella flexneri.福氏志贺菌流行克隆中新出现的一种耐药性血清型 X 变种。
J Clin Microbiol. 2010 Feb;48(2):419-26. doi: 10.1128/JCM.00614-09. Epub 2009 Dec 2.
4
Shifting prevalence of major diarrheal pathogens in patients seeking hospital care during floods in 1998, 2004, and 2007 in Dhaka, Bangladesh.1998年、2004年和2007年孟加拉国达卡洪水期间寻求住院治疗患者中主要腹泻病原体的流行情况变化
Am J Trop Med Hyg. 2008 Nov;79(5):708-14.
5
Molecular characterization of multidrug-resistant Shigella species isolated from epidemic and endemic cases of shigellosis in India.从印度志贺氏菌病的流行和地方病例中分离出的多重耐药志贺氏菌属的分子特征。
J Med Microbiol. 2008 Jul;57(Pt 7):856-863. doi: 10.1099/jmm.0.2008/000521-0.
6
A multicentre study of Shigella diarrhoea in six Asian countries: disease burden, clinical manifestations, and microbiology.一项在六个亚洲国家开展的志贺氏菌腹泻多中心研究：疾病负担、临床表现及微生物学
PLoS Med. 2006 Sep;3(9):e353. doi: 10.1371/journal.pmed.0030353.
7
Trend and disease burden of bacillary dysentery in China (1991-2000).中国细菌性痢疾的流行趋势与疾病负担（1991 - 2000年）
Bull World Health Organ. 2006 Jul;84(7):561-8. doi: 10.2471/blt.05.023853.
8
Web-based surveillance and global Salmonella distribution, 2000-2002.基于网络的监测与全球沙门氏菌分布，2000 - 2002年
Emerg Infect Dis. 2006 Mar;12(3):381-8. doi: 10.3201/eid1205.050854.
9
Standardization of pulsed-field gel electrophoresis protocols for the subtyping of Escherichia coli O157:H7, Salmonella, and Shigella for PulseNet.用于脉冲网络（PulseNet）的大肠杆菌O157:H7、沙门氏菌和志贺氏菌分型的脉冲场凝胶电泳方案的标准化。
Foodborne Pathog Dis. 2006 Spring;3(1):59-67. doi: 10.1089/fpd.2006.3.59.
10
Suggestion to supplement Shigella flexneri classification scheme with the subserovar Shigella flexneri 4c: phenotypic characteristics of strains.建议用弗氏志贺菌4c亚种补充弗氏志贺菌分类方案：菌株的表型特征
J Clin Microbiol. 1988 Jun;26(6):1147-9. doi: 10.1128/jcm.26.6.1147-1149.1988.