Sør-Trøndelag University College, Faculty of Health Education and Social Work, Department of Physiotherapy, Trondheim, Norway.
Physiotherapy. 2013 Dec;99(4):311-6. doi: 10.1016/j.physio.2013.04.001. Epub 2013 Jun 10.
To evaluate the long-term effect of high-dose, high-repetition medical exercise therapy (MET) in patients with patellofemoral pain syndrome (PFPS).
Follow-up study one year after completion of a randomized, controlled trial.
Follow-up testing in the primary healthcare physiotherapy clinics, where intervention was undertaken.
Twenty-eight patients with PFPS completed follow-up testing, fourteen in each group.
The groups received three treatments per week for 12 weeks: high-dose, high-repetition MET for the experimental group, and low-dose, low-repetition exercise therapy for the control group.
Pain measured using a visual analogue scale (VAS: 0-10cm), and function measured using a step-down test (numbers of completed step-downs in 30 seconds) and the modified Functional Index Questionnaire (FIQ: 0 points indicates maximal disability, 16 points no disability).
At baseline there were no differences between groups. After intervention, there were statistically significant (p<0.05) and clinically important differences between groups for all outcome parameters, also when adjusting for gender and duration of symptoms: -1.6 for mean pain [95% confidence interval (CI) -2.4 to -0.8], 6.5 for step-down test (95% CI 3.8 to 9.2), and 3.1 for FIQ (95% CI 1.2 to 5.0). At follow-up the differences between groups were maintained and even increased for mean pain and step-down with significant differences (p<0.05) between groups; -1.8 for mean pain (95% CI: -2.7 to -1.0) and 4.5 for step-down test (95%CI: 2.4 to 6.5). The difference between groups for FIQ at follow-up: 1.1 (95% CI: -1.1 to 3.3).
There appear to be long-term effects of high-dose, high-repetition MET in patients with PFPS with respect to pain and functional outcomes. One year after completed intervention the experimental group has continued to improve, while the control group has relapsed. Registered on http://www.clinicaltrials.gov (identifier: NCT01290705).
评估高剂量、高重复度医学运动疗法（MET）对髌股疼痛综合征（PFPS）患者的长期疗效。
随机对照试验完成一年后的随访研究。
在进行干预的初级保健理疗诊所进行随访测试。
28 名 PFPS 患者完成了随访测试，每组 14 名。
两组每周接受 3 次治疗，共 12 周：实验组接受高剂量、高重复度 MET，对照组接受低剂量、低重复度运动疗法。
使用视觉模拟量表（VAS：0-10cm）测量疼痛，使用下台阶测试（30 秒内完成的下台阶次数）和改良功能指数问卷（FIQ：0 分表示最大残疾，16 分表示无残疾）测量功能。
基线时两组间无差异。干预后，所有结局参数均显示组间存在统计学显著（p<0.05）和临床有意义的差异，且对性别和症状持续时间进行了调整：疼痛平均差值为-1.6（95%置信区间[CI]：-2.4 至-0.8），下台阶测试差值为 6.5（95%CI：3.8 至 9.2），FIQ 差值为 3.1（95%CI：1.2 至 5.0）。随访时组间差异仍保持，且疼痛和下台阶测试进一步增加，组间差异具有统计学意义（p<0.05）：疼痛平均差值为-1.8（95%CI：-2.7 至-1.0），下台阶测试差值为 4.5（95%CI：2.4 至 6.5）。随访时 FIQ 组间差值为 1.1（95%CI：-1.1 至 3.3）。
高剂量、高重复度 MET 对 PFPS 患者的疼痛和功能结局似乎有长期效果。干预完成一年后，实验组继续改善，而对照组复发。在 http://www.clinicaltrials.gov 注册（标识符：NCT01290705）。
