Department of Radiology, Washington University School of Medicine, 4525 Scott Avenue, St. Louis, MO 63110, USA.
Angew Chem Int Ed Engl. 2013 Jul 22;52(30):7756-60. doi: 10.1002/anie.201302564. Epub 2013 Jun 13.
Let me get my nanoruler: Activatable probes based on radionuclide and quantum dots (QDs) were constructed using DNA as a linker. Cerenkov radiation from (64)Cu was used to excite the QDs in a distance-dependent manner. The luminescence was lowest nearest to the QD and increased with distance.
基于放射性核素和量子点 (QDs) 的可激活探针是使用 DNA 作为连接物构建的。(64)Cu 的切伦科夫辐射以距离依赖的方式激发 QDs。发光在最接近 QD 的地方最低,并随距离增加而增加。