Department of Periodontology, International University of Catalunya, Barcelona, Spain.
J Periodontol. 2011 Jan;82(1):80-5. doi: 10.1902/jop.2010.100289. Epub 2010 Jul 27.
The goal of this study is to evaluate the degree of staining and clinical efficacy of a chlorhexidine mouthwash with an antidiscoloration system (ADS) versus 0.2% chlorhexidine mouthwash (traditional). Secondary objectives are to evaluate the patient "compliance" factor according to patterns assigned by the clinician and to observe the side effects of the two mouthwashes.
This comparative study is carried out on a sample of 15 non-smoking patients with chronic periodontitis at the Department of Periodontology, the International University of Catalunya, Barcelona, Spain. All patients used either 0.2% chlorhexidine mouthwash (control group = bottle B) or chlorhexidine with ADS (test group = bottle A) for 15 days. Each patient first rinsed with a randomly assigned mouthwash for 15 days followed by a 15-day washout period. Subsequently, each patient used a second mouthwash. Before each cycle, a full dental prophylaxis was performed. The plaque, gingival, and Brecx staining indexes were used.
The results showed less tooth staining with the test group (P <0.01). No statistically significant differences were observed in plaque (P = 0.1496) and gingival indexes (P = 0.1688). Eighty-eight percent of patients followed the instructions outlined in the protocol. In terms of other adverse effects, two patients reported a bad taste with both mouthwashes.
The test group with ADS had less staining than the control group during a usage period of 15 days. However, the two mouthwashes seemed to be equally effective as antiplaque and antigingivitis agents.
本研究旨在评估一种含去色系统(ADS)的洗必泰漱口水与 0.2%洗必泰漱口水(传统)相比的染色程度和临床疗效。次要目标是根据临床医生分配的模式评估患者“依从性”因素,并观察两种漱口水的副作用。
这项比较研究在西班牙巴塞罗那国际加泰罗尼亚大学牙周病科的 15 名非吸烟慢性牙周炎患者中进行。所有患者均使用 0.2%洗必泰漱口水(对照组=B 瓶)或含 ADS 的洗必泰(实验组=A 瓶)15 天。每位患者首先随机使用一种漱口水漱口 15 天,然后进行 15 天的洗脱期。随后,每位患者使用第二种漱口水。在每个周期之前,都要进行全面的牙齿洁治。使用菌斑、牙龈和 Brecx 染色指数进行评估。
结果显示,实验组的牙齿染色程度较低(P<0.01)。菌斑(P=0.1496)和牙龈指数(P=0.1688)无统计学差异。88%的患者遵循了方案中规定的说明。关于其他不良反应,有两名患者报告两种漱口水均有异味。
在 15 天的使用期内,含 ADS 的实验组比对照组染色程度更低。然而,两种漱口水作为抗菌斑和抗牙龈炎药物似乎同样有效。