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[系统性毛细血管渗漏综合征:低白蛋白血症、血液浓缩与休克。1例病例报告]

[Systemic capillary leak syndrome: hypoalbuminemia, hemoconcentration and shock. Presentation of a case].

作者信息

Muñoz-Guillén N M, León-López R, de la Cal-Ramírez M A, Dueñas-Jurado J M

机构信息

Unidad de Cuidados Intensivos, Hospital Cruz Roja, Córdoba, España.

Unidad de Cuidados Intensivos, Hospital Universitario Reina Sofía, Córdoba, España.

出版信息

Semergen. 2014 Mar;40(2):e33-6. doi: 10.1016/j.semerg.2013.01.003. Epub 2013 Jun 13.

Abstract

Systemic capillary leak syndrome is a rare disorder of unknown etiology and often recurrent episodes characterized by increased capillary permeability that allows a leakage of fluid and proteins from the circulatory system to the interstitial space leading to shock and massive edema. The lack of recognition of this disease may be due to its unespecific signs and symptons of presentation, its rapid clinical progression and high mortality of the acute episodes. General physicians are usually the first to evaluate patients with this kind of disorder, either in the pre-hospital situation, hospital emergency units or even (in the milder cases) in the health centers. Its poor outcome and the improvement in the prognosis, if appropriate treatment is initiated, leads us to emphasize the importance of recognizing this pathology in order to start the appropriate intensive care and emergency treatment.

摘要

系统性毛细血管渗漏综合征是一种病因不明的罕见疾病,常反复发作,其特征是毛细血管通透性增加,导致液体和蛋白质从循环系统渗漏到间质间隙,进而引发休克和大量水肿。对这种疾病认识不足可能是由于其临床表现缺乏特异性、临床进展迅速以及急性发作时死亡率高。全科医生通常是最早评估这类疾病患者的人,无论是在院前情况、医院急诊科,甚至(在病情较轻的情况下)在健康中心。其预后不佳,而如果启动适当治疗则预后会改善,这促使我们强调认识这种病症的重要性,以便启动适当的重症监护和紧急治疗。

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