Department of Otolaryngology-Head and Neck Surgery, Drexel University College of Medicine, Philadelphia, Pennsylvania 19103, USA.
J Voice. 2013 Jul;27(4):486-94. doi: 10.1016/j.jvoice.2013.03.001. Epub 2013 Jun 12.
The importance of laryngopharyngeal reflux (LPR) is acknowledged widely. However, controversy remains regarding pathophysiology, diagnosis, and treatment. This review addresses current literature from late 2009 through the first half of 2012 and complements our previous review of literature from 2006 through the middle of 2009. Both reviews highlight controversies and current research.
Although controversies have not been resolved fully, additional research has expanded approaches to diagnosis and treatment of LPR. Recent studies shed additional light on pathophysiology. New imaging techniques have been introduced and they prove particularly useful in assessing LPR. Research has improved the understanding of the value of selected acid measurement techniques. The efficacy of treatment remains controversial.
LPR clearly is an important entity. However, disagreements persist regarding optimal diagnosis techniques, criteria of normalcy, and treatment efficacy. Additional studies are encouraged to further our understanding of pathophysiology, diagnosis, treatment, and the long-term effects of LPR and LPR treatment.
喉咽反流(LPR)的重要性已得到广泛认可。然而,其发病机制、诊断和治疗仍存在争议。本综述讨论了 2009 年末至 2012 年上半年的最新文献,并补充了我们之前对 2006 年至 2009 年年中文献的综述。这两份综述都强调了争议和当前的研究。
尽管争议尚未完全解决,但更多的研究扩大了 LPR 的诊断和治疗方法。最近的研究进一步阐明了发病机制。已经引入了新的成像技术,它们在评估 LPR 方面特别有用。研究提高了对选择酸测量技术价值的理解。治疗的疗效仍存在争议。
LPR 显然是一个重要的实体。然而,对于最佳诊断技术、正常标准和治疗效果仍存在分歧。鼓励进一步开展研究,以加深我们对 LPR 和 LPR 治疗的发病机制、诊断、治疗以及长期影响的理解。