DNA Tumor Virus Section, Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 209892, USA.
Virology. 2013 Oct;445(1-2):11-20. doi: 10.1016/j.virol.2013.05.012. Epub 2013 Jun 14.
Viruses belonging to the Papillomaviridae family have been isolated from a variety of mammals, birds and non-avian reptiles. It is likely that most, if not all, amniotes carry a broad array of viral types. To date, the complete genomic sequence of more than 240 distinct viral types has been characterized at the nucleotide level. The analysis of this sequence information has begun to shed light on the evolutionary history of this important virus family. The available data suggests that many different evolutionary mechanisms have influenced the papillomavirus phylogenetic tree. Increasing evidence supports that the ancestral papillomavirus initially specialized to infect different ecological niches on the host. This episode of niche sorting was followed by extensive episodes of co-speciation with the host. This review attempts to summarize our current understanding of the papillomavirus evolution.
乳头瘤病毒科的病毒已从多种哺乳动物、鸟类和非鸟类爬行动物中分离出来。很可能，如果不是所有的话，大多数羊膜动物都携带广泛的病毒类型。迄今为止，已有超过 240 种不同病毒类型的完整基因组序列在核苷酸水平上得到了描述。对这些序列信息的分析开始揭示这个重要病毒家族的进化历史。现有数据表明，许多不同的进化机制影响了乳头瘤病毒的系统发育树。越来越多的证据支持这样一种观点，即祖先乳头瘤病毒最初专门感染宿主的不同生态位。这种生态位分化的事件之后，是与宿主的广泛协同进化。本文综述试图总结我们目前对乳头瘤病毒进化的理解。
