Yamada M, Koeda T, Kikuchi H, Nasu M, Isagozawa S, Mukaida H, Yosida H, Ahsan R, Otokida K, Kato M
Second Department of Internal Medicine, Iwate Medical University School of Medicine.
Kokyu To Junkan. 1990 Jun;38(6):571-6.
The present study was performed to elucidate peripheral hemodynamic changes, especially, digital blood flow, caused by an air-cooled cold test. Experiments were carried out by placing the subject's left hand in a box that was kept at a temperature of about 18 degrees C by air-cooling. At the same time, the digital blood flow, digital blood pressure, compliances of the peripheral resistance and capacitance vessels were measured. These parameters were measured on the left forefinger of the cooled side, and also on the opposite side according to Kato's method at 3 points, 1) at normal condition (before cooling stated). 2) 30 seconds after the cooling began and 3) 10 minutes after the cooling began. The following results were obtained; 1) The systemic blood pressure, digital blood pressure and heart rate showed no statistically significant differences in measurements taken at the above three stages. 2) The mean value of the digital blood flow was found to have increased after 30 seconds, and to have decreased after 10 minutes of cooling. Statistically, significant differences were noted at the above three stages. 3) The mean value of the peripheral vascular resistance was found to have increased after 30 seconds, and to have decreased after 10 minutes. 4) Compliances of the peripheral resistance vessel and capacitance vessel showed no significant changes on either side except between normal condition and after 10 minutes of cooling.
本研究旨在阐明风冷冷试验引起的外周血流动力学变化，尤其是指端血流量。通过将受试者左手置于一个通过风冷保持在约18摄氏度的盒子中进行实验。同时，测量指端血流量、指端血压、外周阻力血管和容量血管的顺应性。这些参数在受冷侧的左手食指上测量，并且根据加藤的方法在对侧的三个点进行测量，1）在正常状态下（开始冷却前）。2）冷却开始后30秒和3）冷却开始后10分钟。得到以下结果：1）在上述三个阶段进行的测量中，全身血压、指端血压和心率没有统计学上的显著差异。2）发现指端血流量的平均值在30秒后增加，在冷却10分钟后减少。在上述三个阶段有统计学上的显著差异。3）发现外周血管阻力的平均值在30秒后增加，在10分钟后减少。4）外周阻力血管和容量血管的顺应性在两侧均无显著变化，除了正常状态和冷却10分钟后之间。
