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病例报告621。一名28岁女性的多发性骨髓瘤(IgD型)。

Case report 621. Multiple myeloma (IgD) in a 28-year-old woman.

作者信息

Hermann G, Abdelwahab I F, Berson B D, Greenberg M L, Palestro C J

机构信息

Department of Radiology, Mount Sinai Hospital, New York, New York.

出版信息

Skeletal Radiol. 1990;19(5):379-81.

PMID:2377908
Abstract

A 28-year-old woman with IgD myeloma was described. The patient presented with pain in the anterior wall of the chest, and tenderness over the ribs, thoracic spine, and right shoulder. A radionuclide bone scan showed increased uptake along the costochondral junctions, ribs, and shoulders, with the diffuse uptake in the costochondral junction being typical for costochondritis. Skeletal survey revealed small lucencies in the ribs, humeri, and shoulders, characteristic of MM. The patient's young age made the diagnosis of MM unlikely. The scintigraphic finding, typical of costochondritis, must be an extremely unusual pattern in MM since we were unable to find a similar case in the literature. It is speculated that MM may have been induced by chemical exposure.

摘要

报道了一名28岁的IgD骨髓瘤女性患者。该患者表现为胸前壁疼痛,肋骨、胸椎和右肩部有压痛。放射性核素骨扫描显示肋软骨关节、肋骨和肩部摄取增加,肋软骨关节处的弥漫性摄取是肋软骨炎的典型表现。骨骼检查发现肋骨、肱骨和肩部有小透亮区,这是多发性骨髓瘤的特征。患者年轻,多发性骨髓瘤的诊断不太可能。闪烁扫描结果是肋软骨炎的典型表现,在多发性骨髓瘤中一定是一种极其不寻常的模式,因为我们在文献中未能找到类似病例。推测多发性骨髓瘤可能是由化学暴露诱发的。

相似文献

1
Case report 621. Multiple myeloma (IgD) in a 28-year-old woman.病例报告621。一名28岁女性的多发性骨髓瘤(IgD型)。
Skeletal Radiol. 1990;19(5):379-81.
2
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引用本文的文献

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Advanced myeloma masquerading as chronic shoulder pain in a 48-year-old man: a diagnostic dilemma.48 岁男性,以慢性肩部疼痛为表现的高级别多发性骨髓瘤:诊断困境。
BMJ Case Rep. 2020 May 27;13(5):e231219. doi: 10.1136/bcr-2019-231219.
2
Plasma cell myeloma in unusually young patients: a report of two cases and review of the literature.异常年轻患者的浆细胞骨髓瘤:两例报告及文献复习
Skeletal Radiol. 1995 Jan;24(1):47-51. doi: 10.1007/BF02425947.
3
Multiple myeloma presenting as extramedullary plasmacytoma of the thyroid, advanced grade II-III plasmablastic type.

本文引用的文献

1
IgD myeloma. A report of 4 new cases.IgD骨髓瘤。4例新病例报告。
S Afr Med J. 1982 Mar 13;61(11):407-10.
2
Human immunoglobulins: classes, subclasses, genetic variants, and idiotypes.人免疫球蛋白:类别、亚类、基因变体和独特型。
Adv Immunol. 1973;16:1-59. doi: 10.1016/s0065-2776(08)60295-3.
3
A case of IgD myeloma presenting as diffuse osteosclerosis.一例表现为弥漫性骨硬化的IgD骨髓瘤病例。
多发性骨髓瘤表现为甲状腺髓外浆细胞瘤,高级别II-III级浆母细胞型。
Skeletal Radiol. 1995 May;24(4):314-6. doi: 10.1007/BF00198425.
J Clin Pathol. 1988 May;41(5):486-9. doi: 10.1136/jcp.41.5.486.
4
IgD multiple myeloma. Review of 133 cases.IgD型多发性骨髓瘤。133例病例回顾。
Arch Intern Med. 1975 Jan;135(1):87-93.
5
Multiple myeloma: review of 869 cases.多发性骨髓瘤:869例病例回顾
Mayo Clin Proc. 1975 Jan;50(1):29-40.
6
Osteosclerotic myeloma with polyneuropathy and ectopic secretion of calcitonin.骨硬化性骨髓瘤伴多发性神经病及降钙素异位分泌
Eur J Cancer (1965). 1978 Feb;14(2):133-40. doi: 10.1016/0014-2964(78)90171-8.