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激光辅助无缺血时间部分腹腔镜肾切除术治疗肾细胞癌。

Laser-supported partial laparoscopic nephrectomy for renal cell carcinoma without ischaemia time.

机构信息

University Medical Center Göttingen, Department of Urology, Georg-August-University, Robert-Koch-Str. 40, 37075, Göttingen, Alemanya.

出版信息

BMC Urol. 2013 Jun 20;13:31. doi: 10.1186/1471-2490-13-31.

Abstract

BACKGROUND

To date, elective nephron-sparing surgery is an established method for the exstirpation of renal tumors. While open partial nephrectomy remains the reference standard of the management of renal masses, laparoscopic partial nephrectomy (LPN) continues to evolve. Conventional techniques include clamping the renal vessels risking ischaemic damage of the clamped organ. Thus, new techniques are needed that combine a sufficient tissue incision for exstirpation of the tumor with an efficient coagulation to assure haemostasis and abandon renal vessel clamping in LPN. Laser-excision of renal tumors during laparoscopic surgery seems to be a logical solution.

METHODS

We performed nephron-sparing surgery without clamping of the renal vessels in 11 patients with a renal tumor in exophytic position (mean size 32 mm, ranging 8-45 mm) by laser-supported LPN.

RESULTS

Regular ultrasound monitoring and insertion of a temporary drainage showed no evidence of postoperative hemorrhage. All tumors were removed with a histopathologically confirmed surrounding margin of normal renal tissue (R0 resection). Serum creatinine, hemoglobin, and hematocrit were nearly unaltered before and after surgery.

CONCLUSIONS

The experience won in these patients have confirmed that laser-assisted LPN without clamping of the renal vessels could be a safe and gentle alternative to classic partial nephrectomy in patients with exophytic position of renal tumors.

摘要

背景

迄今为止,选择性保肾手术是切除肾肿瘤的一种既定方法。虽然开放性部分肾切除术仍然是管理肾肿块的参考标准,但腹腔镜部分肾切除术(LPN)仍在不断发展。传统技术包括夹闭肾血管,从而有导致被夹闭器官缺血损伤的风险。因此,需要结合足够的组织切除肿瘤和有效的止血来确保止血并在 LPN 中放弃肾血管夹闭的新技术。腹腔镜手术中激光切除肾肿瘤似乎是一种合理的解决方案。

方法

我们对 11 名患有外生性肾肿瘤的患者(平均大小为 32 毫米,范围为 8-45 毫米)进行了不夹闭肾血管的保肾手术,采用激光辅助 LPN。

结果

定期超声监测和插入临时引流管显示术后无出血证据。所有肿瘤均通过激光辅助 LPN 切除,病理检查证实周围有正常肾组织(R0 切除)。手术前后血清肌酐、血红蛋白和血细胞比容几乎没有变化。

结论

这些患者的经验证实,在肾肿瘤外生性位置的患者中,激光辅助不夹闭肾血管的 LPN 可能是经典部分肾切除术的一种安全、温和的替代方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4bbf/3706310/98e0bffe866c/1471-2490-13-31-1.jpg

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