Hamvas Aaron, Deterding Robin, Balch William E, Schwartz David A, Albertine Kurt H, Whitsett Jeffrey A, Cardoso Wellington V, Kotton Darrell N, Kourembanas Stella, Hagood James S
Washington University School of Medicine, St. Louis Children's Hospital, St. Louis, Missouri.
Pediatr Pulmonol. 2014 Apr;49(4):400-9. doi: 10.1002/ppul.22805. Epub 2013 Jun 24.
A multi-disciplinary scientific conference focused on diffuse and interstitial lung diseases in children was held in La Jolla, CA in June 2012. The conference brought together clinicians (including Pediatric and Adult Pulmonologists, Neonatologists, Pathologists, and Radiologists), clinical researchers, basic scientists, government agency representatives, patient advocates, as well as children affected by diffuse lung disease (DLD) and their families, to review recent scientific developments and emerging concepts in the pathophysiology of childhood DLD. Invited speakers discussed translational approaches, including genetics and proteomics, epigenetics and epigenomics, models of DLD, including animal models and induced pluripotent stem cells, and regenerative medicine approaches. The presentations of the invited speakers are summarized here.
2012年6月，一场聚焦于儿童弥漫性和间质性肺病的多学科科学会议在加利福尼亚州拉霍亚举行。会议汇聚了临床医生（包括儿科和成人肺科医生、新生儿科医生、病理学家和放射科医生）、临床研究人员、基础科学家、政府机构代表、患者权益倡导者，以及受弥漫性肺病（DLD）影响的儿童及其家庭，共同回顾儿童DLD病理生理学的最新科学进展和新兴概念。受邀演讲者讨论了转化医学方法，包括遗传学和蛋白质组学、表观遗传学和表观基因组学、DLD模型，包括动物模型和诱导多能干细胞，以及再生医学方法。在此总结受邀演讲者的发言内容。
