在体内，白细胞介素-1可增强针对感染的免疫反应的特异性和非特异性分支。
In vivo IL-1 potentiates both specific and non-specific arms of immune response to infection.
作者信息
Cheers C, Zhan Y F, Egan P J
机构信息
Department of Microbiology, University of Melbourne, Parkville, Victoria, Australia.
出版信息
Immunology. 1990 Jul;70(3):411-3.
Abstract
Injection of 10(5) U interleukin-1 (IL-1) 4 hr before intravenous infection with Listeria monocytogenes hastens recovery of mice. This is accompanied not only by early stimulation of colony-forming cells in the spleen to levels higher than those in untreated, infected mice but also by accelerated activation of lymphokine-producing, specific T lymphocytes.
摘要
在静脉注射感染单核细胞增生李斯特菌前4小时注射10(5)单位白细胞介素-1（IL-1）可加速小鼠康复。这不仅伴随着脾脏中集落形成细胞的早期刺激，使其水平高于未治疗的感染小鼠，还伴随着产生淋巴因子的特异性T淋巴细胞的加速激活。
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本文引用的文献
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Immunoregulation by macrophages: differential secretion of prostaglandin E and interleukin 1 during infection with Salmonella enteritidis.巨噬细胞的免疫调节作用：肠炎沙门氏菌感染期间前列腺素E和白细胞介素1的差异分泌
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Interleukin-1.白细胞介素-1
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The relative importance of blood monocytes and fixed macrophages to the expression of cell-mediated immunity to infection.血液单核细胞和固定巨噬细胞在细胞介导的抗感染免疫表达中的相对重要性。
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