MidAtlantic Retina, The Retina Service of Wills Eye Institute, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.
Curr Opin Ophthalmol. 2013 Sep;24(5):407-14. doi: 10.1097/ICU.0b013e328363829b.
Outer retinal degenerations such as retinitis pigmentosa can cause profound vision loss. Various treatment strategies are being pursued to potentially restore functional vision in these patients.
Advances in retinal prostheses have restored some vision in patients previously blind from retinitis pigmentosa. Optogenetics is another area that shows promise for restoration of vision. Transcorneal electrostimulation shows some efficacy to treat these patients as well.
We review recent advances in optogenetics, visual prosthesis and electrostimulation to treat outer retinal degenerations.
像色素性视网膜炎这样的外层视网膜变性会导致严重的视力丧失。目前正在探索各种治疗策略，以期为这些患者恢复功能性视力。
视网膜假体的进步已经使以前因色素性视网膜炎失明的患者恢复了部分视力。光遗传学是另一个有希望恢复视力的领域。经角膜电刺激也显示出治疗这些患者的一些效果。
我们回顾了光遗传学、视觉假体和电刺激治疗外层视网膜变性的最新进展。
