遗传学因素在预防医学中的作用。

Genetic parts to a preventive medicine whole.

机构信息

Department of Molecular and Experimental Medicine and the Scripps Translational Science Institute, The Scripps Research Institute, La Jolla, CA 92037, USA.

出版信息

Genome Med. 2013 Jun 27;5(6):54. doi: 10.1186/gm458. eCollection 2013.

DOI:10.1186/gm458

PMID:23806045

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3706981/

Abstract

UNLABELLED

Integration of clinical evaluations and whole-genome sequence data from eight individuals in a recent study demonstrates that genetic and clinical information can be combined and applied to preventive medicine. Statistical and graphical tools were developed to assess and visualize the genetic risk of common chronic conditions and to show the changes in disease risk that result from monitoring clinical symptoms over time. This approach provides a direction to consider in the adoption of genetic information in health care, but, like all provocative scientific articles, it raises as many questions as it answers.

PLEASE SEE RELATED RESEARCH

http://genomemedicine.com/content/5/6/58.

摘要

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最近的一项研究整合了来自八个人的临床评估和全基因组序列数据，证明了遗传和临床信息可以结合并应用于预防医学。开发了统计和图形工具来评估和可视化常见慢性疾病的遗传风险，并显示随着时间的推移监测临床症状导致的疾病风险变化。这种方法为在医疗保健中采用遗传信息提供了一个考虑方向，但和所有有争议的科学文章一样，它提出的问题和答案一样多。