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低浓度苯乙烯暴露工人外周血淋巴细胞中的姐妹染色单体交换。

Sister chromatid exchanges induced in peripheral lymphocytes of workers exposed to low concentrations of styrene.

作者信息

Yager J W, Paradisin W M, Symanski E, Rappaport S M

机构信息

Department of Biomedical and Environmental Health Sciences, University of California, Berkeley 94720.

出版信息

Prog Clin Biol Res. 1990;340C:347-56.

PMID:2381933
Abstract

This study employed a longitudinal sampling design to obtain measurements of exposure and exhaled air from all members of a cohort several times over the course of one year. Styrene in exhaled air correlated well with styrene in breathing zone air. Both smoking and exposure to styrene appear to have contributed significantly and separately to increased SCEs. Early results imply that SCEs were somewhat more highly correlated with styrene in exhaled air than in breathing zone air.

摘要

本研究采用纵向抽样设计,在一年的时间里多次对一组人群的所有成员进行接触量和呼出空气的测量。呼出空气中的苯乙烯与呼吸带空气中的苯乙烯相关性良好。吸烟和接触苯乙烯似乎都分别对姐妹染色单体互换(SCE)增加有显著影响。早期结果表明,SCE与呼出空气中苯乙烯的相关性略高于与呼吸带空气中苯乙烯的相关性。

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