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低浓度苯乙烯暴露工人外周血淋巴细胞中的姐妹染色单体交换。

Sister chromatid exchanges induced in peripheral lymphocytes of workers exposed to low concentrations of styrene.

作者信息

Yager J W, Paradisin W M, Symanski E, Rappaport S M

机构信息

Department of Biomedical and Environmental Health Sciences, University of California, Berkeley 94720.

出版信息

Prog Clin Biol Res. 1990;340C:347-56.

PMID:2381933
Abstract

This study employed a longitudinal sampling design to obtain measurements of exposure and exhaled air from all members of a cohort several times over the course of one year. Styrene in exhaled air correlated well with styrene in breathing zone air. Both smoking and exposure to styrene appear to have contributed significantly and separately to increased SCEs. Early results imply that SCEs were somewhat more highly correlated with styrene in exhaled air than in breathing zone air.

摘要

本研究采用纵向抽样设计,在一年的时间里多次对一组人群的所有成员进行接触量和呼出空气的测量。呼出空气中的苯乙烯与呼吸带空气中的苯乙烯相关性良好。吸烟和接触苯乙烯似乎都分别对姐妹染色单体互换(SCE)增加有显著影响。早期结果表明,SCE与呼出空气中苯乙烯的相关性略高于与呼吸带空气中苯乙烯的相关性。

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1
Sister chromatid exchanges induced in peripheral lymphocytes of workers exposed to low concentrations of styrene.低浓度苯乙烯暴露工人外周血淋巴细胞中的姐妹染色单体交换。
Prog Clin Biol Res. 1990;340C:347-56.
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Sister-chromatid exchanges in lymphocytes are increased in relation to longitudinally measured occupational exposure to low concentrations of styrene.
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Chromosome aberrations and sister chromatid exchanges in styrene-exposed workers with reference to their smoking habits.接触苯乙烯工人的染色体畸变和姐妹染色单体交换及其吸烟习惯
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Studies of the induction of chromosomal aberration and sister chromatid exchange in rats exposed to styrene by inhalation.关于吸入苯乙烯的大鼠染色体畸变和姐妹染色单体交换诱导情况的研究。
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Sister-chromatid exchanges in lymphocytes from styrene-exposed boat builders.接触苯乙烯的造船工人淋巴细胞中的姐妹染色单体交换
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[Study of cytogenetic damages in peripheral blood of styrene exposed workers].[苯乙烯暴露工人外周血细胞遗传学损伤的研究]
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Analysis of chromosomes in peripheral blood lymphocytes of styrene-exposed workers.苯乙烯接触工人外周血淋巴细胞染色体分析。
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Chromosome aberrations, micronuclei and sister-chromatid exchanges in blood lymphocytes after occupational exposure to low levels of styrene.
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引用本文的文献

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Use of the glycophorin A human mutation assay to study workers exposed to styrene.使用血型糖蛋白A人类突变试验研究接触苯乙烯的工人。
Environ Health Perspect. 1993 Mar;99:297-301. doi: 10.1289/ehp.9399297.
2
Chromosome aberrations and micronuclei in lymphocytes of workers exposed to low and medium levels of styrene.接触低、中度苯乙烯的工人淋巴细胞中的染色体畸变和微核
Int Arch Occup Environ Health. 1992;64(3):209-15. doi: 10.1007/BF00380911.