Allah K C, Kossoko H, Assi Djè Bi Djè V, Yéo S, Richard Kadio M
Service de chirurgie plastique reconstructrice et esthétique, chirurgie de la main et brûlologie, CHU de Treichville, Abidjan 01, Côte-d'Ivoire.
Rev Stomatol Chir Maxillofac Chir Orale. 2013 Jun;114(3):184-6. doi: 10.1016/j.revsto.2013.02.003. Epub 2013 Mar 26.
Rhinoscleroma is a chronic granulomatous respiratory tract disease. The initial lesion site is often intra-nasal. Giant tumor presentations are rare. The authors report a case of extensive nasal rhinoscleroma.
A 35-year-old African male patient consulted for a large tumor of the nose. The tumor had appeared 25 years before; the initial lesion site was intra-nasal. It presented as a small non-obstructive growth. The tumor was removed 20 years before, and recurred in an exophytic presentation. The main tumor was associated to peripheral, peri-nasal, and upper lip nodules. There was a central granuloma, bleeding on contact. Nasal obstruction was complete. The histological and bacteriological examination of a biopsy specimen confirmed the diagnosis of rhinoscleroma. Trimethoprim-sulfamethoxazole was effective on the infection.
Rhinoscleroma is frequently located on the nasal mucosa, but extra-nasal giant tumor presentations are rare. It can involve the whole respiratory tract. It is endemic in developing countries. Sporadic cases have been described in non-endemic areas, among migrants. The diagnosis is proved by histology. Specific and early antibiotic therapy is effective. It avoids surgical mutilation, sequels, and recurrence.
鼻硬结病是一种慢性肉芽肿性呼吸道疾病。初始病变部位常位于鼻腔内。巨大肿瘤表现罕见。作者报告一例广泛鼻腔鼻硬结病病例。
一名35岁非洲男性患者因鼻部巨大肿瘤前来就诊。肿瘤于25年前出现；初始病变部位在鼻腔内。起初表现为一个小的无阻塞性肿物。该肿瘤于20年前切除，之后以息肉样表现复发。主要肿瘤伴有外周、鼻周及上唇结节。有一个中央肉芽肿，触之易出血。鼻腔完全阻塞。活检标本的组织学和细菌学检查确诊为鼻硬结病。复方新诺明对感染有效。
鼻硬结病常位于鼻黏膜，但鼻外巨大肿瘤表现罕见。它可累及整个呼吸道。在发展中国家为地方病。在非地方病地区的移民中也有散发病例报道。诊断靠组织学证实。特异性早期抗生素治疗有效。可避免手术致残、后遗症及复发。
