Khalili Maryam, Eshghyar Nosratollah, Ensani Fereshteh, Shakib Pouyan Amini
Department of Oral and Maxillofacial Pathology, Faculty of Dentistry, Tehran University of Medical Sciences, Tehran, Iran.
J Res Med Sci. 2012 Nov;17(11):1082-5.
Synovial sarcoma (SS) is a relatively common soft tissue tumor but only 6%-7% of cases are diagnosed in the head and neck region. It typically occurs in young adults and is slightly more common in males. The most common sites in the head and neck region are hypopharynx and parapharyngeal spaces. However, SS can also occur in tonsils, tongue, and orofacial soft tissues. It is not difficult to diagnose SS microscopically with its classic biphasic appearance, but the diagnosis of monophasic forms is more challenging especially in unusual locations. In this article, we report a rare case of monophasic SS of the mandible. The clinical, histopathological, and immunohistochemical features are discussed and compared with previously reported cases in the literature. To our knowledge, only six primary involvements have been reported in the jaws. Therefore, our case represents the seventh reported case of SS in the area.
滑膜肉瘤（SS）是一种相对常见的软组织肿瘤，但仅有6%-7%的病例发生于头颈部区域。它通常发生于年轻人，男性略为多见。头颈部区域最常见的部位是下咽和咽旁间隙。然而，滑膜肉瘤也可发生于扁桃体、舌及口腔颌面部软组织。滑膜肉瘤具有典型的双相外观，在显微镜下不难诊断，但其单相型的诊断更具挑战性，尤其是在不寻常的部位。在本文中，我们报告了一例罕见的下颌骨单相型滑膜肉瘤病例。对其临床、组织病理学和免疫组化特征进行了讨论，并与文献中先前报道的病例进行了比较。据我们所知，颌骨原发性滑膜肉瘤仅有6例报道。因此，我们的病例是该区域报道的第7例滑膜肉瘤病例。
