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基于光电子系统的深吸气屏气技术在颅外立体定向治疗中的应用。

Deep inspiration breath-hold technique guided by an opto- electronic system for extracranial stereotactic treatments.

机构信息

Medical Physics Unit, European Insitute of Oncology, Milano, Italy.

出版信息

J Appl Clin Med Phys. 2013 Jul 8;14(4):4087. doi: 10.1120/jacmp.v14i4.4087.

Abstract

The purpose of this work was to evaluate the intrapatient tumor position reproducibility in a deep inspiration breath-hold (DIBH) technique based on two infrared optical tracking systems, ExacTrac and ELITETM, in stereotactic treatment of lung and liver lesions. After a feasibility study, the technique was applied to 15 patients. Each patient, provided with a real-time visual feedback of external optical marker displacements, underwent a full DIBH, a free-breathing (FB), and three consecutive DIBH CT-scans centered on the lesion to evaluate the tumor position reproducibility. The mean reproducibility of tumor position during repeated DIBH was 0.5 ± 0.3 mm in laterolateral (LL), 1.0 ± 0.9 mm in anteroposterior (AP), and 1.4 ± 0.9 mm in craniocaudal (CC) direction for lung lesions, and 1.0 ± 0.6 mm in LL, 1.1 ± 0.5 mm in AP, and 1.2 ± 0.4 mm in CC direction for liver lesions. Intra- and interbreath-hold reproducibility during treatment, as determined by optical markers displacements, was below 1 mm and 3 mm, respectively, in all directions for all patients. Optically-guided DIBH technique provides a simple noninvasive method to minimize breathing motion for collaborative patients. For each patient, it is important to ensure that the tumor position is reproducible with respect to the external markers configuration.

摘要

这项工作的目的是评估两种红外光学跟踪系统(ExacTrac 和 ELITETM)在基于深吸气屏气(DIBH)技术中患者内肿瘤位置的重复性,该技术用于立体定向治疗肺部和肝脏病变。在可行性研究之后,该技术应用于 15 名患者。每位患者都提供了外部光学标记位移的实时视觉反馈,进行了完整的 DIBH、自由呼吸(FB)和三次以病变为中心的连续 DIBH CT 扫描,以评估肿瘤位置的可重复性。在重复 DIBH 期间,肿瘤位置的平均可重复性在肺部病变的横侧(LL)方向为 0.5±0.3mm,前后(AP)方向为 1.0±0.9mm,头侧尾侧(CC)方向为 1.4±0.9mm;在肝脏病变的 LL 方向为 1.0±0.6mm,AP 方向为 1.1±0.5mm,CC 方向为 1.2±0.4mm。在所有方向上,所有患者的光学标记位移确定的治疗期间的 intra- 和 interbreath-hold 可重复性均低于 1mm 和 3mm。光学引导的 DIBH 技术为协作患者提供了一种简单的无创方法,可最大程度地减少呼吸运动。对于每位患者,重要的是要确保肿瘤位置相对于外部标记配置具有可重复性。

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