连续体模型在肌腱病理研究中的应用——目前进展如何？
Continuum model of tendon pathology - where are we now?
机构信息
Department of Clinical Therapies, University of Limerick, Limerick, Ireland.
出版信息
Int J Exp Pathol. 2013 Aug;94(4):242-7. doi: 10.1111/iep.12029.
Abstract
Chronic tendon pathology is a common and often disabling condition, the causes of which remain poorly understood. The continuum model of tendon pathology was proposed to provide a model for the staging of tendon pathology and to assist clinicians in managing this often complex condition (Br. J. Sports Med., 43, 2009, 409). The model presents clinical, histological and imaging evidence for the progression of tendon pathology as a three-stage continuum: reactive tendinopathy, tendon disrepair and degenerative tendinopathy. It also provides clinical information to assist in identifying the stage of pathology, in addition to proposed treatment approaches for each stage. The usefulness of such a model is determined by its ability to incorporate and inform new and emerging research. This review examines the degree to which recent research supports or refutes the continuum model and proposes future directions for clinical and research application of the model.
摘要
慢性肌腱病是一种常见且常导致残疾的疾病，其病因仍知之甚少。肌腱病连续体模型的提出旨在为肌腱病的分期提供一个模型，并帮助临床医生管理这种常见的复杂疾病（Br. J. Sports Med.，43，2009，409）。该模型提供了肌腱病进展的临床、组织学和影像学证据，作为一个三阶段连续体：反应性肌腱病、肌腱修复不良和退行性肌腱病。它还提供了有助于确定病理阶段的临床信息，以及每个阶段的建议治疗方法。这种模型的有用性取决于其纳入和告知新出现的研究的能力。本综述考察了最近的研究在多大程度上支持或反驳了连续体模型，并为该模型在临床和研究中的应用提出了未来的方向。
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