Di Grazia S, Succi G, Fragetta F, Perrotta R E
G Chir. 2013 May-Jun;34(5-6):149-52. doi: 10.11138/gchir/2013.34.5.149.
The giant cell tumor of tendon sheath (GCTTS) is the most common benign neoplasm in the hand after the ganglion cyst. Several hypotheses were formulated about the etiological factors of these tumors, but still there is not a common opinion on etiology, prognostic factors and recurrence rate. This article presents a review of literature of the last 15 years about GCTTS to assess the demographic, clinical and histological profile. We compared the information obtained from literature with our experience of 64 cases between 2000 and 2012. Our study showed similar results to those reported in literature, except for the recurrence rate: only 3 cases (4.7%) of 64 patients reported recurrence (versus about 15% on average in literature). Among the various possible factors that predispose to recurrence, it is necessary that the surgeon ensures complete excision of the tumor and removal of any residual satellite nodules. Although the marginal excision is the treatment of choice, it is often difficult to perform due to for the location and the strict adherence of the tumor to the tendon or neurovascular bundles. We used in all cases a magnifying loupe to help a careful research of satellite lesions and to respect surrounding structures.
腱鞘巨细胞瘤（GCTTS）是手部继腱鞘囊肿之后最常见的良性肿瘤。关于这些肿瘤的病因因素提出了几种假说，但在病因、预后因素和复发率方面仍未达成共识。本文对过去15年有关GCTTS的文献进行综述，以评估其人口统计学、临床和组织学特征。我们将从文献中获得的信息与我们在2000年至2012年间64例病例的经验进行了比较。我们的研究结果与文献报道相似，但复发率除外：64例患者中只有3例（4.7%）报告复发（而文献中平均约为15%）。在各种可能导致复发的因素中，外科医生必须确保肿瘤的完整切除并清除任何残留的卫星结节。尽管边缘切除是首选治疗方法，但由于肿瘤的位置以及与肌腱或神经血管束的紧密粘连，往往难以实施。我们在所有病例中都使用了放大放大镜，以帮助仔细查找卫星病灶并保护周围结构。
