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一项关于牙买加青少年 2 型糖尿病和心血管疾病风险的横断面研究。

A cross-sectional study of Jamaican adolescents' risk for type 2 diabetes and cardiovascular diseases.

机构信息

Department of Dietetics and Nutrition and Hospitality Administration, School of Family, Consumer, and Nutrition Sciences, Northern Illinois University, DeKalb, Illinois, USA.

出版信息

BMJ Open. 2013 Jul 11;3(7). doi: 10.1136/bmjopen-2013-002817. Print 2013.

Abstract

OBJECTIVES

To compare obese versus non-obese Jamaican adolescents' risk for type 2 diabetes (T2D) and cardiovascular diseases (CVDs); and to explore a suitable and economical method of screening for these risk factors in the school settings.

DESIGN

A descriptive cross-sectional study of adolescents' risk for T2D and CVD. All the participants were examined at their respective schools.

SETTING

Jamaica, West Indies.

POPULATION

276 Jamaican adolescents aged 14-19 years, randomly selected from grades 9 to 12 from 10 high schools on the island and included both boys and girls. All ethnicities on the island were represented.

MAIN OUTCOME MEASURES

High fasting blood glucose, total cholesterol, glycated haemoglobin (HbA1c), blood pressure, body mass index (BMI), waist circumference, waist-to-hip ratio, family history of obesity, T2D and CVDs, low physical activity, and presence of Acanthosis Nigricans. All blood measures were analysed using the finger prick procedure.

RESULTS

Waist circumference, waist-to-hip ratio, Acanthosis Nigricans, total cholesterol, family history of T2D and blood pressure were the strongest predictors of BMI (p=0.001). Over one-third of the participants were overweight. Jamaican adolescent females had a significantly higher number of risk factors and were less physically active than males (p<0.05). Over 80% of participants reported ≥3 risk factors for T2D and CVD. Participants with BMI ≥25 reported five or more risk factors. One-third of the overweight participants were classified with metabolic syndrome.

CONCLUSIONS

Jamaican adolescents are at risk of T2D and CVD. Family history of disease and anthropometric measures identified more participants at risk than did the blood measures. Jamaican adolescent females reported more risk factors for T2D and CVD as compared to males. Collection of this type of data was feasible within the school settings. All data were collected in 1 day per school. Intervention measures are needed to educate Jamaican adolescents to reduce overweight and subsequently the risk factors.

摘要

目的

比较肥胖和非肥胖牙买加青少年患 2 型糖尿病(T2D)和心血管疾病(CVD)的风险;并探索一种在学校环境中筛查这些风险因素的合适和经济的方法。

设计

一项关于青少年患 T2D 和 CVD 风险的描述性横断面研究。所有参与者都在各自的学校接受检查。

地点

牙买加,西印度群岛。

人群

276 名年龄在 14-19 岁的牙买加青少年,从岛上 10 所高中的 9 至 12 年级中随机抽取,包括男孩和女孩。岛上所有种族都有代表。

主要观察指标

空腹血糖高、总胆固醇、糖化血红蛋白(HbA1c)、血压、体重指数(BMI)、腰围、腰臀比、肥胖家族史、T2D 和 CVD、低身体活动和黑棘皮症。所有血液指标均采用指尖采血法进行分析。

结果

腰围、腰臀比、黑棘皮症、总胆固醇、T2D 家族史和血压是 BMI 的最强预测因子(p=0.001)。超过三分之一的参与者超重。牙买加青少年女性的风险因素明显多于男性,身体活动也明显少于男性(p<0.05)。超过 80%的参与者报告有≥3 个 T2D 和 CVD 的风险因素。BMI≥25 的参与者报告有 5 个或更多的风险因素。三分之一的超重参与者被归类为代谢综合征。

结论

牙买加青少年有患 T2D 和 CVD 的风险。与血液指标相比,疾病家族史和人体测量指标可以识别出更多的风险人群。与男性相比,牙买加青少年女性报告的 T2D 和 CVD 风险因素更多。在学校环境中收集此类数据是可行的。每个学校只需一天就可以收集所有数据。需要采取干预措施,教育牙买加青少年减轻体重,从而降低风险因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a3e/3710979/919004525506/bmjopen2013002817f01.jpg

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