先天性肥厚性幽门狭窄中的血浆胃泌素。一个被否定的假说。
Plasma gastrin in congenitial hypertrophic pyloric stenosis. A hypothesis disproved.
作者信息
Rogers I M, Drainer I K, Moore M R, Buchanan K D
出版信息
Arch Dis Child. 1975 Jun;50(6):467-71. doi: 10.1136/adc.50.6.467.
Abstract
Fasting plasma gastrin levels were measured in babies with pyloric stenosis and in normal babies of similar age. There was no difference in gastrin levels either before or after operation between the babies with pyloric stenosis and normal babies. Similarly, neither the fasting blood glucose nor the fasting gastric pH of the babies with pyloric stenosis differed significantly from the values obtained in normal babies. Our findings do not support the hypothesis that gastrin in the fasting baby has an aetiological role in the development of hypertrophic pyloric stenosis of infancy. An alternative hypothesis is suggested.
摘要
对患有幽门狭窄的婴儿和年龄相仿的正常婴儿测量了空腹血浆胃泌素水平。患有幽门狭窄的婴儿与正常婴儿在术前和术后的胃泌素水平均无差异。同样，患有幽门狭窄的婴儿的空腹血糖和空腹胃pH值与正常婴儿所测得的值相比也没有显著差异。我们的研究结果不支持这样的假说，即空腹婴儿体内的胃泌素在婴儿肥厚性幽门狭窄的发生中具有病因学作用。本文提出了另一种假说。
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本文引用的文献
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