Li Yanlu, Segers Patrick, Dirckx Joris, Baets Roel
Photonics Research Group, INTEC-department, Ghent University-IMEC, Sint-Pietersnieuwstraat 41, 9000, Ghent, Belgium ; Center for Nano- and Biophotonics (NB-Photonics), Ghent University, Sint-Pietersnieuwstraat 41, 9000, Ghent, Belgium.
Biomed Opt Express. 2013 Jun 27;4(7):1229-35. doi: 10.1364/BOE.4.001229. Print 2013 Jul 1.
Pulse wave velocity (PWV) is an important marker for cardiovascular risk. The Laser Doppler vibrometry has been suggested as a potential technique to measure the local carotid PWV by measuring the transit time of the pulse wave between two locations along the common carotid artery (CCA) from skin surface vibrations. However, the present LDV setups are still bulky and difficult to handle. We present in this paper a more compact LDV system integrated on a CMOS-compatible silicon-on-insulator substrate. In this system, a chip with two homodyne LDVs is utilized to simultaneously measure the pulse wave at two different locations along the CCA. Measurement results show that the dual-LDV chip can successfully conduct the PWV measurement.
脉搏波速度（PWV）是心血管风险的重要标志物。激光多普勒振动测量法已被提议作为一种潜在技术，通过测量沿颈总动脉（CCA）两个位置之间脉搏波从皮肤表面振动的传播时间来测量局部颈动脉PWV。然而，目前的激光多普勒振动测量装置仍然体积庞大且难以操作。我们在本文中展示了一种集成在与CMOS兼容的绝缘体上硅衬底上的更紧凑的激光多普勒振动测量系统。在该系统中，一个带有两个零差激光多普勒振动测量仪的芯片被用于同时测量沿CCA两个不同位置的脉搏波。测量结果表明，双激光多普勒振动测量仪芯片能够成功进行PWV测量。
