Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
J Korean Med Sci. 2013 Jul;28(7):1083-8. doi: 10.3346/jkms.2013.28.7.1083. Epub 2013 Jul 3.
The incidence of overall cancer has increased over time. The incidence of top-ranking cancers has changed in the 1990s and the 2000s. However, few studies have evaluated the trends in metastatic skin cancers during this period. We evaluated the recent trends in incidence, peak age and location of metastatic skin cancers from 1991 to 2010. This 20-yr survey was divided into two decades to determine the trends by comparing the statistics. Out of 694,466 outpatients (1991-2010), 174 (0.025%) were diagnosed with metastatic skin cancer. The incidence of metastatic skin cancer increased significantly from 20.64 per 100,000 outpatients in the 1990s to 28.70 per 100,000 outpatients in the 2000s (P = 0.030). The peak age of skin metastasis shifted from the 40s to the 50s in women, and from the 50s to the 60s in men. The percentage of metastatic skin cancers originating from intra-abdominal organs increased from 10% in the 1990s to 23.1% in the 2000s (P = 0.027). The percentage of metastatic skin cancers located on the abdomen increased from 7.1% in the 1990s to 15.4% in the 2000s (P = 0.011). The higher proportion of metastatic skin cancers located on the abdomen may be related to the increase in skin metastases from intra-abdominal organs.
总体癌症的发病率随时间推移而增加。在 20 世纪 90 年代和 21 世纪，排名靠前的癌症的发病率发生了变化。然而，很少有研究评估这一时期转移性皮肤癌的趋势。我们评估了 1991 年至 2010 年期间转移性皮肤癌的发病率、发病高峰年龄和发病部位的最新趋势。这项 20 年的调查分为两个十年，通过比较统计数据来确定趋势。在 694466 名门诊患者（1991-2010 年）中，有 174 人（0.025%）被诊断为转移性皮肤癌。转移性皮肤癌的发病率从 20 世纪 90 年代每 10 万门诊患者 20.64 例显著增加到 21 世纪 00 年代的每 10 万门诊患者 28.70 例（P = 0.030）。女性皮肤转移的发病高峰年龄从 40 多岁转移到 50 多岁，男性则从 50 多岁转移到 60 多岁。源自腹腔内器官的转移性皮肤癌比例从 20 世纪 90 年代的 10%增加到 21 世纪 00 年代的 23.1%（P = 0.027）。源自腹腔内器官的转移性皮肤癌比例从 20 世纪 90 年代的 7.1%增加到 21 世纪 00 年代的 15.4%（P = 0.011）。腹部转移性皮肤癌比例的增加可能与源自腹腔内器官的皮肤转移的增加有关。
