Ostela I, Tenovuo J, Söderling E, Lammi E, Lammi M
Institute of Dentistry, University of Turku, Finland.
Proc Finn Dent Soc. 1990;86(1):9-14.
A chlorhexidine (1%)-sodium fluoride (0.2%) gel applied using a dental tray six times during two consecutive days significantly decreased salivary levels of mutans streptococci but had only a slight effect on salivary levels of lactobacilli. The same gel used as a dentifrice for one week (twice a day) also significantly reduced salivary levels of mutans streptococci. However, this treatment was somewhat less effective than that using trays, on the basis of the ratio of mutans streptococci to total aerobes. With both treatments baseline salivary levels of mutans streptococci were re-attained after 70 days. One day after the gel treatment, mutans streptococci were unable to adhere to plastic strips (Dentocult SM Strip mutans) but detectable growth was found on mitis-salivarius-bacitracin agar. This suggests that not only are numbers of mutans streptococci reduced after chlorhexidine-sodium fluoride gel treatment but also mutans streptococci adherence.
在连续两天内使用牙托六次涂抹洗必泰(1%)-氟化钠(0.2%)凝胶,可显著降低变形链球菌的唾液水平,但对唾液中乳酸菌水平的影响甚微。同一凝胶用作牙膏使用一周(每天两次)也能显著降低变形链球菌的唾液水平。然而,基于变形链球菌与总需氧菌的比例,这种治疗方法的效果略逊于使用牙托的方法。两种治疗方法在70天后,变形链球菌的唾液基线水平均恢复到之前状态。凝胶治疗一天后,变形链球菌无法附着在塑料条上(Dentocult SM Strip mutans),但在轻唾-杆菌肽琼脂上发现了可检测到的生长。这表明,洗必泰-氟化钠凝胶治疗后不仅变形链球菌数量减少,而且变形链球菌的黏附性也降低。