Järvinen H, Tenovuo J, Huovinen P
Antimicrobial Research Laboratory, National Public Health Institute, Turku, Finland.
Antimicrob Agents Chemother. 1993 May;37(5):1158-9. doi: 10.1128/AAC.37.5.1158.
The susceptibility of Streptococcus mutans to chlorhexidine and to six commonly used, systemic antibacterial agents (amoxicillin, cefuroxime, penicillin, sulfamethoxazole-trimethoprim, tetracycline, and erythromycin) was studied for 424 clinical isolates from 116 children and students. The MIC of chlorhexidine for all isolates was < or = 1 micrograms/ml. No resistance to the other antimicrobial agents was detected. Although widely exposed to various antimicrobial agents, S. mutans has remained susceptible to common antimicrobial agents, most importantly to chlorhexidine.
对从116名儿童和学生中分离出的424株变形链球菌临床菌株，研究了其对氯己定以及六种常用全身抗菌剂（阿莫西林、头孢呋辛、青霉素、磺胺甲恶唑-甲氧苄啶、四环素和红霉素）的敏感性。所有菌株对氯己定的最低抑菌浓度均≤1微克/毫升。未检测到对其他抗菌剂的耐药性。尽管变形链球菌广泛暴露于各种抗菌剂，但它对常见抗菌剂仍保持敏感，最重要的是对氯己定敏感。
