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[先天与后天:表观遗传学在精神疾病病因学中的重要性]

[Nature meets nurture: the importance of epigenetics for the aetiology of psychiatric diseases].

作者信息

Buchholz V, Kotsiari A, Bleich S, Frieling H

机构信息

Klinik für Psychiatrie, Sozialpsychiatrie und Psychotherapie, Medizinische Hochschule Hannover.

出版信息

Fortschr Neurol Psychiatr. 2013 Jul;81(7):368-80. doi: 10.1055/s-0033-1335739. Epub 2013 Jul 15.

DOI:10.1055/s-0033-1335739
PMID:23856942
Abstract

A successful therapy requires an understanding and investigation of the aetiology of a disease. Psychiatric diseases represent a special challenge, because environmental factors may play a crucial role in their development as well as possible physiological and genetic causes. Therefore, epigenetics has established itself to be a branch of research that studies the effect of environmental factors on the development of psychiatric diseases, leading to promising new approaches for diagnosis and therapy.

摘要

成功的治疗需要对疾病的病因进行理解和调查。精神疾病是一项特殊的挑战,因为环境因素在其发展过程中可能与潜在的生理和遗传因素一样发挥关键作用。因此,表观遗传学已成为一个研究分支,致力于研究环境因素对精神疾病发展的影响,从而为诊断和治疗带来了有前景的新方法。

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