Department of Counseling Psychology, Seoul Cyber University, Seoul, Korea.
Asia Pac Psychiatry. 2013 Jun;5(2):90-100. doi: 10.1111/appy.12070.
There has been plenty of interest in cognitive rehabilitation for schizophrenia here in Korea since the year 2000. But the efficacy studies of cognitive remediation intervention are still deficient. The primary purpose of this study was to develop a computer-assisted cognitive remediation program and conduct a clinical trial in a group of schizophrenic patients.
Sixty patients with schizophrenia were randomly assigned to a computerized cognitive rehabilitation (Cog-trainer) group plus usual rehabilitation (UR) or to a usual rehabilitation (UR) group only. Clinical, neuropsychological and functional outcome variables were assessed at baseline and after intervention. The Cog-trainer group received 20 sessions of computerized cognitive remediation training over 3 months. This training program consists of 10 units, with each unit being divided into three stages: (i) practice; (ii) application; and (iii) advanced.
Compared to the UR group, the Cog-trainer exhibited a significant improvement in attention, concentration and working memory. The Cog-trainer group also showed improvement in the work quality subscale of the work behavior inventory. However, there were no significant benefits of computerized cognitive remediation where symptoms were concerned.
These results indicate that computerized cognitive rehabilitation training can contribute to an improvement in the cognitive function of people with schizophrenia. The changes in cognitive outcomes can also contribute to improvement in job functioning. Further study of generalization to other functional outcome measures will be necessary. Long-term follow-up studies are needed to confirm the maintenance of such improvements.
自 2000 年以来，韩国一直对精神分裂症的认知康复产生浓厚兴趣。但认知矫正干预的疗效研究仍然不足。本研究的主要目的是开发一种计算机辅助认知矫正程序，并在一组精神分裂症患者中进行临床试验。
将 60 例精神分裂症患者随机分为计算机认知矫正（Cog-trainer）组加常规康复（UR）组或仅常规康复（UR）组。在基线和干预后评估临床、神经心理学和功能结局变量。Cog-trainer 组接受 20 次计算机认知矫正训练，为期 3 个月。该训练计划由 10 个单元组成，每个单元分为三个阶段：（i）练习；（ii）应用；（iii）高级。
与 UR 组相比，Cog-trainer 在注意力、注意力和工作记忆方面有显著改善。Cog-trainer 组在工作行为清单的工作质量子量表上也有改善。然而，在症状方面，计算机认知矫正并没有显著的益处。
这些结果表明，计算机认知康复训练可以改善精神分裂症患者的认知功能。认知结果的变化也有助于改善工作功能。有必要进一步研究对其他功能结局测量的推广。需要进行长期随访研究以确认这些改善的维持。
