Hamdard Institute of Medical Sciences and Research, Hamdard University, New Delhi 110062, India.
Biomed Res Int. 2013;2013:932863. doi: 10.1155/2013/932863. Epub 2013 Jun 20.
Xanthelasma palpebrarum (XP) are yellow plaques that occur most commonly near the inner canthus of the eyelid and are often associated with atherosclerosis, dyslipidemia, and coronary artery disease. This study was planned to address the issue of associated cardiovascular morbidity in xanthelasma patients attending our cardiac clinic.
A total of 61 patients were detected to be having xanthelasma and constituted the study group. The control group constituted of 130 apparently normal individuals. Each patient underwent detailed history, examination, and investigations.
The most prevalent age group was 40 to 60 years. Males outnumbered females. A percentage of 39.3% of cases had concomitant nicotine addiction. Dyslipidemia was present in 60% of cases, hypertension in 37.7%, prehypertension in 8.77%, diabetes mellitus in 18.03%, and prediabetes in 26.3%. Smokers and obese patients with xanthelasma had a higher prevalence of hypertension. Coronary artery disease (CAD) was found in 6.56% of XP cases. The waist circumference and diastolic blood pressures were significantly higher in XP patients.
A significant number of cases of xanthelasma palpebrarum are combined with smoking, central obesity, hypertension, diabetes mellitus, and dyslipidemia which are the major risk factors for CAD. Efforts should be made to rule out the same in high-risk xanthelasma subjects.
眼睑黄色瘤（XP）是最常见于眼睑内眦附近的黄色斑块，常与动脉粥样硬化、血脂异常和冠心病有关。本研究旨在探讨在我院心脏科就诊的黄色瘤患者中与心血管发病率相关的问题。
共发现 61 例 XP 患者，将其设为研究组。对照组由 130 名看似正常的个体组成。每位患者均接受详细的病史、检查和检查。
最常见的年龄组为 40 至 60 岁。男性多于女性。39.3%的病例同时存在尼古丁成瘾。60%的病例存在血脂异常，37.7%的病例存在高血压，8.77%的病例存在高血压前期，18.03%的病例存在糖尿病，26.3%的病例存在糖尿病前期。有黄色瘤的吸烟者和肥胖者高血压的患病率更高。6.56%的 XP 病例发现有冠心病。XP 患者的腰围和舒张压明显较高。
相当数量的眼睑黄色瘤病例与吸烟、中心性肥胖、高血压、糖尿病和血脂异常有关，这些都是冠心病的主要危险因素。应努力在高危黄色瘤患者中排除这些因素。
