Onesti Maria G, Fino Pasquale, Fioramonti Paolo, Amorosi Vittoria, Scuderi Nicolò
Department of Plastic, Reconstructive and Aesthetic Surgery, University of Rome "Sapienza", Policlinico Umberto I, Rome, Italy.
Int Wound J. 2015 Aug;12(4):447-50. doi: 10.1111/iwj.12134. Epub 2013 Jul 19.
Malignant degeneration of wounds is rare and often misdiagnosed. Delay in diagnosis may result in a worse prognosis. The aim of this study is to determine the number of skin cancers associated with chronic skin ulcers in our facility over a period of 10 years. Between January 2002 and December 2012, a total of about 1000 patients had consulted with us for chronic wounds, especially of vascular, diabetic and traumatic origin and pressure ulcers. Thirteen skin cancers had been detected: seven squamous cell and five basal cell carcinomas and one melanoma. We highlight how important it is to be aware of the signs suggesting a malignant change and the importance of biopsy at regular intervals during the life cycle of any chronic wound.
伤口恶变罕见且常被误诊。诊断延误可能导致预后更差。本研究的目的是确定我们机构10年间与慢性皮肤溃疡相关的皮肤癌数量。2002年1月至2012年12月期间，共有约1000例患者因慢性伤口前来就诊，尤其是血管性、糖尿病性、创伤性慢性伤口及压疮。共检测到13例皮肤癌：7例鳞状细胞癌、5例基底细胞癌和1例黑色素瘤。我们强调，认识到提示恶变的迹象以及在任何慢性伤口的病程中定期进行活检的重要性。
