Department of Physiology, Institution of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg, Medicinaregatan 11, Box 432, 405 30 Göteborg, Sweden.
Department of Physiology, Institution of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg, Medicinaregatan 11, Box 432, 405 30 Göteborg, Sweden.
Clin Nutr. 2014 Jun;33(3):471-7. doi: 10.1016/j.clnu.2013.06.017. Epub 2013 Jul 4.
BACKGROUND & AIMS: Quantitative magnetic resonance (QMR) has previously been shown to both overestimate and underestimate average fat mass (FM) in humans. Eight-electrode bioelectrical impedance analysis (BIA) has previously been found biased as well as successfully validated. We report cross-sectional accuracy of QMR and eight-electrode BIA evaluated with air displacement plethysmography (ADP) as reference method.
Fat mass and fat free mass (FFM) by QMR and eight-electrode BIA were evaluated against ADP as reference in 38 normal weight and 30 obese women. Total body water estimates by QMR and eight-electrode BIA were compared.
Fat mass was overestimated by QMR (1 ± 2 kg, p < 0.001) and was underestimated by eight-electrode BIA (1 ± 3 kg, p = 0.03, Bonferroni adjusted p = 0.29) in normal weight women. Fat mass was underestimated by both QMR (2 ± 2 kg, p < 0.001) and eight-electrode BIA (9 ± 3 kg, p < 0.001) in obese women. Fat free mass biases were of similar magnitude but in opposite direction to FM biases. Total body water estimates were larger by eight-electrode BIA compared to QMR (1-10 kg).
Fat mass and FFM by QMR were both biased but in opposite directions in both normal weight and obese women. Eight-electrode BIA FM and FFM estimates were imprecise and biased in obese women. Thus, QMR is more precise and more accurate than eight-electrode BIA for estimating body composition in women, but is not accurate enough to be used for individual single assessment of body composition.
定量磁共振（QMR）先前已被证明会高估和低估人体平均脂肪量（FM）。先前发现八电极生物电阻抗分析（BIA）存在偏差，但已成功验证。我们报告了使用空气置换体描记法（ADP）作为参考方法评估 QMR 和八电极 BIA 的横断面准确性。
在 38 名正常体重和 30 名肥胖女性中，使用 QMR 和八电极 BIA 评估脂肪质量和无脂肪质量（FFM）与 ADP 作为参考的结果。比较 QMR 和八电极 BIA 估计的总体水分。
在正常体重女性中，QMR 高估了 FM（1 ± 2 公斤，p < 0.001），而八电极 BIA 低估了 FM（1 ± 3 公斤，p = 0.03，Bonferroni 调整后的 p = 0.29）。在肥胖女性中，QMR（2 ± 2 公斤，p < 0.001）和八电极 BIA（9 ± 3 公斤，p < 0.001）均低估了 FM。FM 偏倚的大小相似，但方向相反。与 QMR 相比，八电极 BIA 估计的总体水分更大（1-10 公斤）。
QMR 的 FM 和 FFM 均存在偏差，但在正常体重和肥胖女性中方向相反。肥胖女性的八电极 BIA FM 和 FFM 估计不准确且存在偏差。因此，与八电极 BIA 相比，QMR 更精确、更准确地估计女性身体成分，但不够准确，不能用于个体单次身体成分评估。
