Department of Bioorganic Chemistry, Faculty of Chemistry, Wrocław University of Technology, Wybrzeże Wyspiańskiego 27, 50-370 Wroclaw, Poland.
Molecules. 2013 Jul 18;18(7):8473-84. doi: 10.3390/molecules18078473.
The development of nanotechnology is responsible for an increase in the achievements in medical diagnostics and in the preparation of new therapeutic vehicles. In particular, magnetic nanoparticles with a modified surface are a very attractive alternative to deliver therapeutic agents. We describe the modification of the surface of the iron oxide nanoparticles with aminophosphonic acids by applying the classic hydrophosphonylation approach.
纳米技术的发展推动了医学诊断和新型治疗载体的制备方面的进展。特别是,经过表面改性的磁性纳米颗粒是一种很有吸引力的治疗药物载体。我们通过应用经典的膦酰化方法,用氨基膦酸对氧化铁纳米颗粒的表面进行改性。