文献检索，用中文搜 PubMed

Suppr 超能文献

核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Clin Exp Pharmacol Physiol. 1975 May-Jun;2(3):269-76. doi: 10.1111/j.1440-1681.1975.tb03032.x.

The influence of cholinoceptor stimulation and cholinoceptor blockade on the mitotic rate in epithelial cells lining the crypts of Lieberkühn in rat jejunum was studied. 2. Cholinoceptor stimulation, either by injection of carbachol or by inhibition of acetylcholinesterase enzymes resulted in an increase in the mitotic rate. This increase in mitotic rate was blocked by tubocurarine, but not by atropine or hexamethonium. Atropine by itself increased the mitotic rate whereas tubocurarine alone or hexamethonium along decreased the mitotic rate. 3. The influence of atropine on crypt cell proliferation appears to involve an adrenergic mechanism since it is blocked by phentolamine.

研究了胆碱受体激动和胆碱受体阻断对大鼠空肠利伯库恩隐窝上皮细胞有丝分裂率的影响。2. 通过注射卡巴胆碱或抑制乙酰胆碱酯酶来刺激胆碱受体，均导致有丝分裂率增加。这种有丝分裂率的增加被筒箭毒碱阻断，但不受阿托品或六甲铵阻断。阿托品本身可增加有丝分裂率，而单独使用筒箭毒碱或六甲铵则会降低有丝分裂率。3. 阿托品对隐窝细胞增殖的影响似乎涉及肾上腺素能机制，因为它被酚妥拉明阻断。

Clin Exp Pharmacol Physiol. 1975 May-Jun;2(3):269-76. doi: 10.1111/j.1440-1681.1975.tb03032.x.

The influence of cholinoceptor stimulation and cholinoceptor blockade on the mitotic rate in epithelial cells lining the crypts of Lieberkühn in rat jejunum was studied. 2. Cholinoceptor stimulation, either by injection of carbachol or by inhibition of acetylcholinesterase enzymes resulted in an increase in the mitotic rate. This increase in mitotic rate was blocked by tubocurarine, but not by atropine or hexamethonium. Atropine by itself increased the mitotic rate whereas tubocurarine alone or hexamethonium along decreased the mitotic rate. 3. The influence of atropine on crypt cell proliferation appears to involve an adrenergic mechanism since it is blocked by phentolamine.

研究了胆碱受体激动和胆碱受体阻断对大鼠空肠利伯库恩隐窝上皮细胞有丝分裂率的影响。2. 通过注射卡巴胆碱或抑制乙酰胆碱酯酶来刺激胆碱受体，均导致有丝分裂率增加。这种有丝分裂率的增加被筒箭毒碱阻断，但不受阿托品或六甲铵阻断。阿托品本身可增加有丝分裂率，而单独使用筒箭毒碱或六甲铵则会降低有丝分裂率。3. 阿托品对隐窝细胞增殖的影响似乎涉及肾上腺素能机制，因为它被酚妥拉明阻断。