Michigan Nanotechnology Institute for Medicine and Biological Sciences, University of Michigan Medical School, Ann Arbor, Michigan 48109-5648, USA.
Nat Rev Immunol. 2013 Aug;13(8):592-605. doi: 10.1038/nri3488.
Nanotechnology uses the unique properties of objects that function as a unit within the overall size range of 1-1,000 nanometres. The engineering of nanostructure materials, including nanoparticles, nanoemulsions or nanotubules, holds great promise for the development of new immunomodulatory agents, as such nanostructures can be used to more effectively manipulate or deliver immunologically active components to target sites. Successful applications of nanotechnology in the field of immunology will enable new generations of vaccines, adjuvants and immunomodulatory drugs that aim to improve clinical outcomes in response to a range of infectious and non-infectious diseases.
纳米技术利用的是在 1-1000 纳米的整体尺寸范围内作为一个单元发挥作用的物体的独特性质。纳米结构材料的工程，包括纳米粒子、纳米乳剂或纳米管，为开发新的免疫调节剂带来了巨大的希望，因为这种纳米结构可以更有效地操纵或递送到目标部位的免疫活性成分。纳米技术在免疫学领域的成功应用将使新一代疫苗、佐剂和免疫调节剂得以应用，旨在改善对一系列感染性和非传染性疾病的临床疗效。
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