中性粒细胞与淋巴细胞比值和冠状动脉血流缓慢之间的关系。
Relationship between neutrophil to lymphocyte ratio and slow coronary flow.
作者信息
Doğan Mehmet, Akyel Ahmet, Çimen Tolga, Bilgin Murat, Sunman Hamza, Kasapkara Haci Ahmet, Arslantaş Uğur, Yayla Kadriye Gayretli, Açıkel Sadık, Yeter Ekrem
机构信息
Department of Cardiology, Dışkapı Yıldırım Beyazıt Education and Research Hospital, Ankara, Turkey
Department of Cardiology, Dışkapı Yıldırım Beyazıt Education and Research Hospital, Ankara, Turkey.
出版信息
Clin Appl Thromb Hemost. 2015 Apr;21(3):251-4. doi: 10.1177/1076029613498814. Epub 2013 Jul 26.
OBJECTIVES
We evaluated the relationship between neutrophil to lymphocyte ratio (NLR) and slow coronary flow (SCF).
METHODS
A total of 180 participants were recruited to the present study. Of all the participants, 82 patients were with SCF and 98 participants were with normal coronary arteries. Basal characteristics were recorded. Coronary flow was quantified by thrombolysis in myocardial infarction frame count.
RESULTS
Basal characteristics were similar between the 2 groups. The NLR was significantly higher in the SCF group when compared to the control group (2.3 ± 0.8 and 1.5 ± 0.4 respectively, P < .001). In multiple logistic regression analysis, NLR remained as the independent predictor of SCF (P < 0.001).
CONCLUSIONS
Our findings showed that NLR was significantly higher in the SCF group when compared to the control group with normal coronary arteries. We also showed that NLR was related to the presence of SCF rather than the extent of SCF. Besides these findings, we also showed the NLR as an independent predictor of SCF.
目的
我们评估了中性粒细胞与淋巴细胞比值（NLR）和冠状动脉血流缓慢（SCF）之间的关系。
方法
本研究共招募了180名参与者。在所有参与者中，82例患者存在冠状动脉血流缓慢，98名参与者冠状动脉正常。记录基础特征。通过心肌梗死溶栓帧数来量化冠状动脉血流。
结果
两组之间的基础特征相似。与对照组相比，冠状动脉血流缓慢组的NLR显著更高（分别为2.3±0.8和1.5±0.4，P<0.001）。在多因素逻辑回归分析中，NLR仍然是冠状动脉血流缓慢的独立预测因子（P<0.001）。
结论
我们的研究结果表明，与冠状动脉正常的对照组相比，冠状动脉血流缓慢组的NLR显著更高。我们还表明，NLR与冠状动脉血流缓慢的存在有关，而非与冠状动脉血流缓慢的程度有关。除了这些发现外，我们还表明NLR是冠状动脉血流缓慢的独立预测因子。
Zotero 插件