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中国中医药治疗获得性免疫缺陷综合征:机遇、进展与挑战。

Treatment of acquired immunodeficiency syndrome with Chinese medicine in China: opportunity, advancement and challenges.

机构信息

Department of AIDS Treatment and Research Center, the First Affiliated Hospital of Henan University of Traditional Chinese Medicine, Zhengzhou 450000, China.

出版信息

Chin J Integr Med. 2013 Aug;19(8):563-7. doi: 10.1007/s11655-013-1552-1. Epub 2013 Jul 29.

DOI:10.1007/s11655-013-1552-1
PMID:23893134
Abstract

Chinese medicine (CM) has been used in the treatment of human immunodeficiency virus (HIV) infection and acquired immunodeficiency syndrome (AIDS) for 30 years and the demonstrated therapeutic effects of CM, such as reducing plasma HIV viral load, increasing CD4(+)T cell counts, promoting immunity reconstitution, ameliorating symptoms and signs, improving the health related quality of life (HRQOL) and counteracting against the effects of anti-retroviral drugs, were summarized and reviewed in this article. The authors point out that it had been a good opportunity to use CM for the treatment of HIV infection and AIDS in the past and also there are huge challenges ahead for CM research and clinicians to discover more effective CM and its underlying mechanisms for treatment of AIDS.

摘要

中医药治疗人类免疫缺陷病毒(HIV)感染和获得性免疫缺陷综合征(AIDS)已经有 30 年的历史,中医药的治疗作用,如降低血浆 HIV 病毒载量、增加 CD4+T 细胞计数、促进免疫重建、改善症状和体征、提高健康相关生活质量(HRQOL)和对抗抗逆转录病毒药物的影响,在本文中得到了总结和回顾。作者指出,过去中医药治疗 HIV 感染和 AIDS 是一个很好的机会,而中医药研究和临床医生也面临着巨大的挑战,需要发现更有效的中医药及其治疗 AIDS 的潜在机制。

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本文引用的文献

1
Fighting against acquired immunodeficiency syndrome with Chinese medicine: a perspective from China.运用中医药防治艾滋病:来自中国的视角。
Chin J Integr Med. 2011 May;17(5):323-5. doi: 10.1007/s11655-011-0723-1. Epub 2011 May 25.
2
Overview of antiretroviral treatment in China: advancement and challenges.中国抗逆转录病毒治疗概述:进展与挑战。
Chin Med J (Engl). 2011 Feb;124(3):440-4.
3
[Effect of long-term highly active antiretroviral therapy on abnormal immune activation and immune reconstruction in HIV-1 infected individuals].
免疫重建不良的抗反转录病毒治疗后应用免疫增强剂 mianyi 颗粒( mianyi+)的疗效和安全性:一项随机、双盲、多中心、安慰剂对照临床试验。
J Tradit Chin Med. 2022 Jun;42(3):432-438. doi: 10.19852/j.cnki.jtcm.2022.03.010.
4
Chinese herbal medicine for patients living with HIV in Guangxi province, China: an analysis of two registries.中国广西地区艾滋病毒感染者使用中草药情况:两项注册研究分析。
Sci Rep. 2019 Nov 25;9(1):17444. doi: 10.1038/s41598-019-53725-x.
5
Advantages of Chinese Medicine for Patients with Acquired Immunodeficiency Syndrome in Rural Central China.中医对中国中部农村地区获得性免疫缺陷综合征患者的益处。
Chin J Integr Med. 2018 Dec;24(12):891-896. doi: 10.1007/s11655-017-2418-8. Epub 2017 Sep 8.
6
[Comment on the intervention of Traditional Chinese Medicine on survival rates of patients living with human immunodeficiency virus and acquired immune deficiency syndrome].[关于中医对人类免疫缺陷病毒及获得性免疫缺陷综合征患者生存率干预的述评]
J Tradit Chin Med. 2016 Jun;36(3):409-10. doi: 10.1016/s0254-6272(16)30055-3.
7
Survival rate: an indicator of the management of acquired immune deficiency syndrome using Traditional Chinese Medicine.生存率:中医药治疗获得性免疫缺陷综合征的一项指标。
J Tradit Chin Med. 2015 Aug;35(4):473-7. doi: 10.1016/s0254-6272(15)30127-8.
8
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Chin J Integr Med. 2015 Apr;21(4):243-8. doi: 10.1007/s11655-015-2138-x. Epub 2015 Apr 16.
9
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Chin J Integr Med. 2010 Dec;16(6):557-64. doi: 10.1007/s11655-010-0573-2. Epub 2010 Nov 26.
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[Study on the quality of life and influencing factors among people living with AIDS].[艾滋病感染者生活质量及其影响因素研究]
Zhonghua Liu Xing Bing Xue Za Zhi. 2009 Jun;30(6):622-5.
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[Effect of moxibustion on immunological function in the patient of AIDS of spleen-kidney yang-deficiency].[艾灸对艾滋病脾肾阳虚患者免疫功能的影响]
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An investigation into the health-related quality of life of individuals living with HIV who are receiving HAART.对正在接受高效抗逆转录病毒治疗的艾滋病毒感染者的健康相关生活质量进行的一项调查。
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