Wu X Y, Ohinmaa A, Johnson J A, Veugelers P J
Department of Public Health Sciences, School of Public Health, University of Alberta, 8303-112 Street, Edmonton, AB, T6G 2 T4, Canada,
Qual Life Res. 2014 Mar;23(2):393-402. doi: 10.1007/s11136-013-0479-5. Epub 2013 Jul 27.
The objective of the study is to derive a scoring system for the EQ-5D child-friendly version (EQ-5D-Y) from a population-based sample of children based on their own health state assessments on the descriptive system and the visual analogue scale (VAS).
We used data from the 2008 and 2010 Raising Healthy Eating and Active Living Kids in Alberta surveys of grade five students aged primarily 10-11 years and their parents in the Canadian province of Alberta. We applied a random split sample approach. Two-thirds of the sample (modeling sample) was used for the estimation of the EQ-5D-Y VAS. The remaining one-third sample (validation sample) was used for the examination of the prediction accuracy of the estimation model. Multilevel linear regression was used to estimate EQ-5D-Y VAS score and produce EQ-5D-Y index values from the children's self-rated states described in the EQ-5D-Y and the accompanying VAS values.
The mean EQ-5D-Y VAS-based index value was 0.891 (SD 0.133) in the modeling sample and 0.885 (SD 0.134) in the validation sample. The own VAS-based index generally showed logical consistency, with lower values for health states that were logically worse. There was no statistically significant difference between the observed and the predicted VAS values in this sample.
This study elicited a value set for health states defined by the EQ-5D-Y that is based on respondents' own VAS ratings from a large representative sample of Canadian children. Future study is needed to validate this type of value set among different age groups of children.
本研究的目的是基于儿童对描述系统和视觉模拟量表(VAS)的自身健康状况评估,从基于人群的儿童样本中推导儿童友好版EQ-5D(EQ-5D-Y)的评分系统。
我们使用了2008年和2010年艾伯塔省健康饮食与积极生活儿童养育调查的数据,这些数据来自加拿大艾伯塔省主要为10 - 11岁的五年级学生及其父母。我们采用了随机分割样本方法。三分之二的样本(建模样本)用于估计EQ-5D-Y VAS。其余三分之一的样本(验证样本)用于检验估计模型的预测准确性。多级线性回归用于估计EQ-5D-Y VAS得分,并根据EQ-5D-Y中描述的儿童自评状态和随附的VAS值生成EQ-5D-Y指数值。
在建模样本中,基于EQ-5D-Y VAS的平均指数值为0.891(标准差0.133),在验证样本中为0.885(标准差0.134)。基于自身VAS的指数总体上显示出逻辑一致性,逻辑上较差的健康状态指数值较低。该样本中观察到的和预测的VAS值之间没有统计学上的显著差异。
本研究得出了一个由EQ-5D-Y定义的健康状态值集,该值集基于来自加拿大儿童的大型代表性样本中受访者自己的VAS评分。未来需要进行研究以在不同年龄组的儿童中验证这种类型的值集。