基于振荡侧壁锐缘的声流微混合器。
An acoustofluidic micromixer based on oscillating sidewall sharp-edges.
机构信息
Department of Engineering Science and Mechanics, The Pennsylvania State University, University Park, PA 16802, USA.
出版信息
Lab Chip. 2013 Oct 7;13(19):3847-52. doi: 10.1039/c3lc50568e.
Abstract
Rapid and homogeneous mixing inside a microfluidic channel is demonstrated via the acoustic streaming phenomenon induced by the oscillation of sidewall sharp-edges. By optimizing the design of the sharp-edges, excellent mixing performance and fast mixing speed can be achieved in a simple device, making our sharp-edge-based acoustic micromixer a promising candidate for a wide variety of applications.
摘要
通过侧壁锐缘振动引起的声流现象，在微流道内实现了快速均匀混合。通过优化锐缘的设计，可以在简单的装置中实现优异的混合性能和快速的混合速度，使得我们基于锐缘的声微混合器成为各种应用的有前途的候选者。
相似文献
1
An acoustofluidic micromixer based on oscillating sidewall sharp-edges.基于振荡侧壁锐缘的声流微混合器。
Lab Chip. 2013 Oct 7;13(19):3847-52. doi: 10.1039/c3lc50568e.
2
A reliable and programmable acoustofluidic pump powered by oscillating sharp-edge structures.一种由振荡锐边结构驱动的可靠且可编程的声流泵。
Lab Chip. 2014 Nov 21;14(22):4319-23. doi: 10.1039/c4lc00806e.
3
Investigation of acoustic streaming patterns around oscillating sharp edges.振荡尖锐边缘周围声流模式的研究。
Lab Chip. 2014 Aug 7;14(15):2824-36. doi: 10.1039/c4lc00191e. Epub 2014 Jun 6.
4
Acoustofluidic devices controlled by cell phones.手机控制的声流控装置。
Lab Chip. 2018 Jan 30;18(3):433-441. doi: 10.1039/c7lc01222e.
5
Integration of acoustic micromixing with cyclic olefin copolymer microfluidics for enhanced lab-on-a-chip applications in nanoscale liposome synthesis.声混频与环烯烃共聚物微流控的集成用于增强纳米级脂质体合成的片上实验室应用。
Biofabrication. 2024 Jul 10;16(4). doi: 10.1088/1758-5090/ad5d19.
6
A multi-vortex micromixer based on the synergy of acoustics and inertia for nanoparticle synthesis.基于声学和惯性协同作用的多涡旋微混合器用于纳米颗粒合成。
Anal Chim Acta. 2023 Jan 25;1239:340742. doi: 10.1016/j.aca.2022.340742. Epub 2022 Dec 22.
7
An acoustofluidic sputum liquefier.一种声流控痰液液化器。
Lab Chip. 2015 Aug 7;15(15):3125-31. doi: 10.1039/c5lc00539f.
8
Cell lysis via acoustically oscillating sharp edges.通过声振荡的锐利边缘裂解细胞。
Lab Chip. 2019 Dec 21;19(24):4021-4032. doi: 10.1039/c9lc00498j. Epub 2019 Nov 13.
9
Selective particle and cell capture in a continuous flow using micro-vortex acoustic streaming.利用微涡旋声流在连续流中进行选择性的颗粒和细胞捕获。
Lab Chip. 2017 May 16;17(10):1769-1777. doi: 10.1039/c7lc00215g.
10
Acoustofluidic enzyme-linked immunosorbent assay (ELISA) platform enabled by coupled acoustic streaming.声流耦合的声流酶联免疫吸附测定（ELISA）平台。
Anal Chim Acta. 2019 Nov 4;1079:129-138. doi: 10.1016/j.aca.2019.05.073. Epub 2019 Jun 1.
引用本文的文献
1
An Acoustofluidic Device for Sample Preparation and Detection of Small Extracellular Vesicles.一种用于小细胞外囊泡样品制备和检测的声流控装置。
Cyborg Bionic Syst. 2025 Jul 17;6:0319. doi: 10.34133/cbsystems.0319. eCollection 2025.
2
Technology Roadmap of Micro/Nanorobots.微纳机器人技术路线图
ACS Nano. 2025 Jul 15;19(27):24174-24334. doi: 10.1021/acsnano.5c03911. Epub 2025 Jun 27.
3
Ultrasound-activated cilia for biofilm control in indwelling medical devices.用于控制植入式医疗器械中生物膜的超声激活纤毛
Proc Natl Acad Sci U S A. 2025 May 6;122(18):e2418938122. doi: 10.1073/pnas.2418938122. Epub 2025 Apr 28.
4
[High stability enhanced ultrasonic microfluidic structure with flexible tip coupled bubbles].具有柔性尖端耦合气泡的高稳定性增强型超声微流体结构
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2024 Oct 25;41(5):919-925. doi: 10.7507/1001-5515.202401076.
5
Characterizing Acoustic Behavior of Silicon Microchannels Separated by a Porous Wall.表征由多孔壁分隔的硅微通道的声学行为。
Micromachines (Basel). 2024 Jun 30;15(7):868. doi: 10.3390/mi15070868.
6
Acoustohydrodynamic micromixers: Basic mixing principles, programmable mixing prospectives, and biomedical applications.声流体动力学微混合器：基本混合原理、可编程混合前景及生物医学应用。
Biomicrofluidics. 2024 Apr 18;18(2):021505. doi: 10.1063/5.0179750. eCollection 2024 Mar.
7
Cavity-agnostic acoustofluidic manipulations enabled by guided flexural waves on a membrane acoustic waveguide actuator.由膜声波导致动器上的引导弯曲波实现的与腔无关的声流体操纵。
Microsyst Nanoeng. 2024 Mar 8;10:33. doi: 10.1038/s41378-023-00643-8. eCollection 2024.
8
Enhanced Performance of an Acoustofluidic Device by Integrating Temperature Control.通过集成温度控制提高声流体装置的性能
Micromachines (Basel). 2024 Jan 27;15(2):191. doi: 10.3390/mi15020191.
9
Particle Tracking and Micromixing Performance Characterization with a Mobile Device.使用移动设备进行粒子跟踪和微混合性能表征
Sensors (Basel). 2023 Dec 18;23(24):9900. doi: 10.3390/s23249900.
10
Design Optimization Method for Large-Size Sidewall-Driven Micromixer to Generate Powerful Swirling Flow.用于产生强旋流的大尺寸侧壁驱动微混合器的设计优化方法
Micromachines (Basel). 2023 Dec 16;14(12):2246. doi: 10.3390/mi14122246.
本文引用的文献
1
Tunable, pulsatile chemical gradient generation via acoustically driven oscillating bubbles.通过声驱动的振荡气泡实现可调谐、脉冲式化学梯度生成。
Lab Chip. 2013 Feb 7;13(3):328-31. doi: 10.1039/c2lc40923b.
2
A droplet-based, optofluidic device for high-throughput, quantitative bioanalysis.基于液滴的光流控装置，用于高通量、定量生物分析。
Anal Chem. 2012 Dec 18;84(24):10745-9. doi: 10.1021/ac302623z. Epub 2012 Nov 27.
3
A single-layer, planar, optofluidic switch powered by acoustically driven, oscillating microbubbles.一种由声学驱动的振荡微气泡驱动的单层平面光流体开关。
Appl Phys Lett. 2012 Oct 1;101(14):141101. doi: 10.1063/1.4742864.
4
Rapid magnetofluidic mixing in a uniform magnetic field.在均匀磁场中快速磁流体混合。
Lab Chip. 2012 Nov 21;12(22):4772-80. doi: 10.1039/c2lc40818j.
5
Exploiting mechanical biomarkers in microfluidics.微流控中的力学生物标志物的开发利用。
Lab Chip. 2012 Oct 21;12(20):4006-9. doi: 10.1039/c2lc90100e.
6
Mechanism of co-nanoprecipitation of organic actives and block copolymers in a microfluidic environment.在微流控环境中有机活性物质和嵌段共聚物的共纳米共沉淀机制。
Nanotechnology. 2012 Sep 21;23(37):375602. doi: 10.1088/0957-4484/23/37/375602. Epub 2012 Aug 24.
7
Single-shot characterization of enzymatic reaction constants Km and kcat by an acoustic-driven, bubble-based fast micromixer.基于声驱动气泡的快速微混合器实现对酶促反应常数 Km 和 kcat 的单次分析。
Anal Chem. 2012 Sep 4;84(17):7495-501. doi: 10.1021/ac301590y. Epub 2012 Aug 14.
8
Oscillating bubbles: a versatile tool for lab on a chip applications.振荡气泡：芯片实验室应用的多功能工具。
Lab Chip. 2012 Nov 7;12(21):4216-27. doi: 10.1039/c2lc40424a.
9
Revisiting lab-on-a-chip technology for drug discovery.重新审视用于药物发现的芯片实验室技术。
Nat Rev Drug Discov. 2012 Aug;11(8):620-32. doi: 10.1038/nrd3799.
10
Surface acoustic wave (SAW) acoustophoresis: now and beyond.表面声波（SAW）声悬浮：现在和未来。
Lab Chip. 2012 Aug 21;12(16):2766-70. doi: 10.1039/c2lc90076a. Epub 2012 Jul 10.
Zotero 插件