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常春藤乙醇提取物的抗炎和抗关节炎特性

The Antiinflammatory and Antiarthritic Properties of Ethanol Extract of Hedera helix.

作者信息

Rai Anuradha

机构信息

Department of Zoology, St. Joseph's College, Darjeeling 734 104, India.

出版信息

Indian J Pharm Sci. 2013 Jan;75(1):99-102. doi: 10.4103/0250-474X.113537.

DOI:10.4103/0250-474X.113537
PMID:23901168
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3719157/
Abstract

The ethanol Hedera helix plant extract was tested for its antiinflammatory properties. Intraperitoneal injections of 7.5 ml/kg wt ethanol extract showed antiinflammatory activity with 88.89% inhibition as compared to reference drug diclofenac, which showed 94.44% inhibition in formalin-induced paw oedema. As formalin-induced paw oedema closely resembles human arthritis, the antiarthritic property of ethanol extract of Hedera helix was also investigated. The visible reduction in arthritic symptoms by extract of Hedera helix suggests the potential of the plant extract against inflammation and arthritis.

摘要

对常春藤乙醇植物提取物的抗炎特性进行了测试。腹腔注射7.5毫升/千克体重的乙醇提取物显示出抗炎活性，与参考药物双氯芬酸相比，抑制率为88.89%，双氯芬酸在福尔马林诱导的爪肿胀中显示出94.44%的抑制率。由于福尔马林诱导的爪肿胀与人类关节炎非常相似，因此还研究了常春藤乙醇提取物的抗关节炎特性。常春藤提取物使关节炎症状明显减轻，表明该植物提取物具有抗炎和抗关节炎的潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eed8/3719157/98c7940338c0/IJPhS-75-99-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eed8/3719157/98c7940338c0/IJPhS-75-99-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eed8/3719157/98c7940338c0/IJPhS-75-99-g002.jpg

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